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Nature 444, 1015-1017 (21 December 2006) | doi:10.1038/4441015a; Published online 21 December 2006

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Ageing: Too fast by mistake

Tom Kirkwood1

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The intricate process of ageing involves numerous physiological pathways, together with genetic and environmental factors. Insight into this complex biology could come from studying a disorder that accelerates ageing.

Contrary to general expectation, human life expectancy in developed countries has not bumped into a ceiling, but continues to increase by around two years per decade1 — or five hours per day. The reason previous forecasts proved wrong is simple.

  1. Tom Kirkwood is in the Centre for Integrated Systems Biology of Ageing and Nutrition, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne NE4 6BE, UK.
    Email: tom.kirkwood@ncl.ac.uk

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