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From the following article:

Early events in the thymus affect the balance of effector and regulatory T cells

Daniel J. Pennington, Bruno Silva-Santos, Tobias Silberzahn, Mónica Escórcio-Correia, Martin J. Woodward, Scott J. Roberts, Adrian L. Smith, P. Julian Dyson & Adrian C. Hayday

Nature 444, 1073-1077(21 December 2006)

doi:10.1038/nature06051

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Activated splenic bold gammadelta cells from Tcrb-/- mice express activated DETC-specific genes and display regulatory potential in vitro.

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Figure 2

bold gammadelta cells from Tcrb-/- and Ptcra-/-mice express Foxp3.

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Figure 3

Ptcra-/- CD4+TCR-alphabetahi thymocytes and splenocytes are enriched for Foxp3+ regulatory cells.

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Figure 4

Trans-conditioning regulates the differential capacity of early thymic progenitors to develop into T cells with regulatory characteristics.

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