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Editorial
Nature 444, 790 (14 December 2006) | doi:10.1038/444790a; Published online 13 December 2006
The elephant in the room
Sooner or later during the life of any drug candidate, there comes the time when it must be administered to humans. Phase I clinical trials, or 'first in man' trials, will always carry an inherent risk; the critical thing is how to manage the risk to the paid participants who volunteer as test subjects.
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