Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 444, 833-834 (14 December 2006) | doi:10.1038/444833a; Published online 13 December 2006
Open Innovation Challenges
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
-
Methods to Analyze Consumer Emotions
The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ...
- More Challenges
- Powered by:
nature jobs
Basic Science Medical Educators
- Texas Tech University Health Sciences Center
- El Paso, Texas, USA
Tenure-Track Faculty Position Experimental Condensed Matter Physics Department of Physics McGill University
- McGill Univerisity
- Montreal, Quebec, Canada
Diabetes: Kicking off the insulin cascade
Catherine Jackson1
Abstract
Inhibition of the insulin-signalling pathway leads to insulin resistance, an early step in the development of type 2 diabetes. A novel family of protein activators seems to act near the pathway's inception.
Many of the cellular processes that are vital for human health are regulated by the insulin/insulin-like growth factor signalling pathway, including glucose homeostasis, fat metabolism, cell growth and differentiation, and ageing1, 2. Defects in this pathway are central to the development of obesity and related diseases such as diabetes, in cancer and in the process of ageing.
- Catherine Jackson is in the Laboratory of Enzymology and Structural Biochemistry, Bat 34, CNRS, 91198 Gif sur Yvette, France.
Email: catherine.jackson@lebs.cnrs-gif.fr
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Research HighlightsNature Chemical Biology News and Views (01 Feb 2007)
V-ATPase: a potential pH sensorNature Cell Biology News and Views (01 Feb 2006)
RESEARCH
Manganese Superoxide Dismutase Affects Cytochrome c Release and Caspase-9 Activation After Transient Focal Cerebral Ischemia in MiceJournal of Cerebral Blood Flow & Metabolism Original Article
Structure of the Sec7 domain of the Arf exchange factor ARNONature Letters to Editor (05 Mar 1998)
See all 11 matches for Research