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Nature 444, 807 (14 December 2006) | doi:10.1038/444807a; Published online 13 December 2006

Open Innovation Challenges

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Animal research: A matter of life and death

Few issues in biology have the power to fire up emotions like the topic of animal research. The public face of the debate is largely characterized by polarized positions: the use of animals in the laboratory is simply either 'all good' or 'all bad'.