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Nature 444, 794-795 (14 December 2006) | doi:10.1038/444794a; Published online 13 December 2006

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When good cholesterol turns bad

Helen Pearson

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Pfizer's heart drug fails clinical trial.

Last week's dramatic failure of a drug trial aimed at boosting 'good' cholesterol is bad news for Pfizer, the world's largest drug company. But will it also dash the hopes of those looking for a new way of preventing heart attacks?

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