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From the following article:

The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites

Kota Arun Kumar, Gen-ichiro Sano, Silvia Boscardin, Ruth S. Nussenzweig, Michel C. Nussenzweig, Fidel Zavala and Victor Nussenzweig

Nature 444, 937-940(14 December 2006)

doi:10.1038/nature05361

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Figure 1

Expression of CS in transgenic mice.

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Figure 2

Circulating CS in the transgenic mice inhibits infectivity of sporozoites.

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Figure 3

CS-Tg mice are tolerant to the H-2Kd restricted CTL epitope of P. yoelii CS.

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Figure 4

CS-Tg mice produce T-cell-independent antibodies to CS.

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Figure 5

Protection mediated by immunization with IrSp in BALB/c and C57BL/6 CS-Tg mice.

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