Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Article
Nature 444, 761-765 (7 December 2006) | doi:10.1038/nature05349;
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
- More Challenges
- Powered by:
nature jobs
Manager for the Recently Established Fly Facility
- Max-Planck-Institute of Immunobiology
- Freiburg Germany
Senior Staff Scientist
- National Institute of Mental Health (NIMH)
- Bethesda, Maryland
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
Transformed, oncogenic precursors, possessing both defining neural-stem-cell properties and the ability to initiate intracerebral tumours, have been identified in human brain cancers. Here we report that bone morphogenetic proteins (BMPs), amongst which BMP4 elicits the strongest effect, trigger a significant reduction in the stem-like, tumour-initiating precursors of human glioblastomas (GBMs).
&
Abstract
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
