Figures and Tables : Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling : Nature

From the following article:

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

Mark A. Daniels, Emma Teixeiro, Jason Gill, Barbara Hausmann, Dominique Roubaty, Kaisa Holmberg, Guy Werlen, Georg A. Holländer, Nicholas R. J. Gascoigne and Ed Palmer

Nature 444, 724-729(7 December 2006)

doi:10.1038/nature05269

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Figure 1

Defining ligand potency and the thymic selection boundary.

Full size figure and legend (199K)

Figure 2

Ligand affinity and contributions of CD8 and TCR to ligand binding.

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Figure 3

Differences in TCR proximal signal induction distinguish positive and negative selecting ligands.

Full size figure and legend (186K)

Figure 4

Differential compartmentalization of early signal intermediates by positive and negative selecting ligands.

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Figure 5

Signalling and compartmentalization profiles are predictive of selection outcome.

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Table 1

Quantification of tetramer binding

Full size table and legend

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