Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 444, 553-555 (30 November 2006) | doi:10.1038/444553a; Published online 29 November 2006
Open Innovation Challenges
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Senior Scientist, Cellular & Molecular Pharmacology
- Cortex Search Inc.
- Vancouver, British Columbia
Apply for PhD Program
- Shinshu University
- Ueda, Nagano 386-8567 Japan
Chemical biology: A broader take on DNA
Aaron M. Leconte1 & Floyd E. Romesberg1
Abstract
Slipping in extra benzene rings creates a broader DNA double helix that is similar to, but different from, natural DNA. Importantly, it can encode more genetic information — and that could have wide implications.
Compared with proteins, which can have any number of jumbled forms, the DNA double helix — that most famous of nature's molecular structures1— is comfortingly regular. Over the past few years, however, Eric Kool and his colleagues have re-engineered this predictable duplex, producing an 'expanded' version that they call xDNA2.
- Aaron M. Leconte and Floyd E. Romesberg are in the Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Correspondence to: Floyd E. Romesberg1 Email: floyd@scripps.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Amplify this! DNA and RNA get a third base pairNature Methods News and Views (01 Sep 2006)
