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Nature 444, 549 (30 November 2006) | doi:10.1038/444549a; Published online 29 November 2006

Understanding cancer

Chris Boshoff1

BOOK REVIEWEDThe Biology of Cancer

by Robert A. Weinberg

Garland Science: 2006. 796 pp. £89.99 $140 (hbk) £41.99 $99 (pbk)

Every cancer researcher knows 'The hallmarks of cancer', an iconic review by Douglas Hanahan and Robert Weinberg (Cell 100, 57–70; 2000) that outlined the principles of tumour development: self-sufficiency in growth signals, insensitivity to antigrowth signals, evading apoptosis, limitless replicative potential, induction of angiogenesis, invasion and metastasis. In The Biology of Cancer, Weinberg has expanded these hallmarks into an alluring text.