Fossils and astronomy provide clues to why species come and go.
doi:10.1038/7112xiiia
Table of contents
Volume 443 Number 7112 ppxiii-722
Top of page
Editorials
A global folly p605
If not a global non-nuclear proliferation regime based on international treaties, then what?
doi:10.1038/443605a
Forgotten plights p605
Ambassador for Earth p606
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News
The fizzle heard around the world p610
North Korea's nuclear test raises more questions than answers. Despite the small size of the blast, Jim Giles and Geoff Brumfiel get little reassurance from the weapon watchers.
doi:10.1038/443610a
Protests mount against Libyan trial p612
Nobel prize blurs boundaries p615
Intelligent design gets political p615
Teaching creationism becomes an election issue in Michigan.
Geoff Brumfiel
doi:10.1038/443615b
Sidelines p616
doi:10.1038/443616a
Hard-hitting endeavour captures Ig Nobel p616
Woodpecker research flies away with alternative prize.
Steve Nadis
doi:10.1038/443616b
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Business
Hell on no wheels p621
The crash of a demonstration train in Germany casts a shadow on magnetic levitation technology. Ned Stafford reports.
doi:10.1038/443621a
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News Features
Oceanography: The real sea change p622
What can pirates' journals and centuries-old cookbooks teach modern-day ecologists? Mark Schrope meets the researchers who trawl history books for deeper insights into marine ecosystems.
Mark Schrope
doi:10.1038/443622a
AIDS in Africa: A question of trust p626
AIDS treatment in South Africa is often a tug-of-war between clinicians and traditional healers. Natasha Bolognesi meets a woman who is uniquely qualified to heal the rift.
Natasha Bolognesi
doi:10.1038/443626a
Depression: Comfortably numb p629
It started life as an anaesthetic, then became a psychedelic club drug. Now researchers think ketamine could hold the key to understanding and treating depression, says Erika Check.
Erika Check
doi:10.1038/443629a
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Correspondence
Biochemistry has outgrown its traditional boundaries p632
Videos have starring role to play in protocol sharing p632
Consistency tests establish empirical generalizations p632
Chimp comparisons won't explain human evolution p632
Science prediction rate would be good in gambling p632
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Books and Arts
Evolution's highest branches p633
An intriguing tour around and, especially, up the tree of life.
doi:10.1038/443633a
Psychoneuroindoctrinology p634
doi:10.1038/443634a
A comprehensive medical history p635
doi:10.1038/443635a
The background buzz p635
doi:10.1038/443635b
Science in culture: A modern megalith p636
Mariko Mori's glass sculpture responds to the death of stars.
Martin Kemp
doi:10.1038/443636a
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News and Views
素粒子物理学：ビッグバンで起こった相転移？
Particle physics: Did the Big Bang boil? p637
Standard theories tell us that, at some point in the Universe's evolution, free quarks and gluons must have become bound together into the hadronic matter we see today. But was this transition abrupt or smooth?
Frank Wilczek
doi:10.1038/443637a
日本語要約 | Full Text | PDF (458K)
進化生物学：全体像をとらえられるようになったショウジョウバエの眼
Evolutionary biology: Fly eyes get the whole picture p638
The compound eyes of ancestral flies picked up only one picture point in each facet. The evolution of a means to split up the light-sensitive cells increased this number to seven, boosting the eye's resolution greatly.
Kevin Moses
doi:10.1038/nature05209
日本語要約 | Full Text | PDF (241K)
50 & 100 years ago p639
doi:10.1038/443639a
日本語要約 | Full Text | PDF (217K)
物理化学：相転移の種をまく
Physical chemistry: Seeds of phase change p641
An effective but counter-intuitive trick to obtain highly ordered protein crystals is to 'seed' particles on disordered, porous surfaces. Computer simulations provide an explanation for the success of this strategy.
Daan Frenkel
doi:10.1038/443641a
日本語要約 | Full Text | PDF (212K)
神経科学：毛細血管の調節機構
Neuroscience: Controlled capillaries p642
The finest scale of blood flow through the brain occurs in capillaries. Suspicions that capillary flow is regulated by cells that put the squeeze on these vessels are now borne out by detailed experiments.
Brian A. MacVicar and Michael W. Salter
doi:10.1038/443642a
日本語要約 | Full Text | PDF (175K)
発生生物学：心臓の変化
Developmental biology: A change of heart p642
地球科学：古代の酸素の増減状況
Earth sciences: Ups and downs of ancient oxygen p643
The latest models suggest that atmospheric oxygen could have fluctuated between high and low concentrations once photosynthesis had evolved. But does the geological evidence really support this?
James F. Kasting
doi:10.1038/443643a
日本語要約 | Full Text | PDF (156K)
生態学：理想自由分布に従った移動
Ecology: Moving to the ideal free home p645
Pike move between two basins of a British lake to maximize their evolutionary fitness. This adaptive behaviour suggests that habitat selection is more significant in population dynamics than was thought.
Douglas W. Morris
doi:10.1038/443645a
日本語要約 | Full Text | PDF (259K)
細胞生物学：ミトコンドリアのシェープアップ
Cell biology: Mitochondria shape up p646
Mitochondria are central to the process of programmed cell death that kills damaged or superfluous cells. Surprisingly, components of the death machinery turn out to be essential for keeping these organelles in shape.
Barbara Conradt
doi:10.1038/443646a
日本語要約 | Full Text | PDF (527K)
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Brief Communications
An accessory chromophore in red vision p649
The rods in salamanders' retinas can co-opt a molecule derived from chlorophyll to detect red light.
T. Isayama, D. Alexeev, C. L. Makino, I. Washington, K. Nakanishi and N. J. Turro
doi:10.1038/443649a
First paragraph | Full Text | PDF (177K) | Supplementary information
Corrigendum p649
doi:10.1038/443649b
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Review
生理：ホスホイノシチドの細胞の制御や膜の動的変化における役割
Phosphoinositides in cell regulation and membrane dynamics p651
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Articles
細胞：ミトコンドリアの形態形成におけるBaxおよびBakの役割
Role of Bax and Bak in mitochondrial morphogenesis p658
Mariusz Karbowski, Kristi L. Norris, Megan M. Cleland, Seon-Yong Jeong and Richard J. Youle
doi:10.1038/nature05111
細胞：eEF3の構造およびE部位からの転移RNAの放出機構
Structure of eEF3 and the mechanism of transfer RNA release from the E-site p663
Christian B. F. Andersen, Thomas Becker, Michael Blau, Monika Anand, Mario Halic, Bharvi Balar, Thorsten Mielke, Thomas Boesen, Jan Skov Pedersen, Christian M. T. Spahn, Terri Goss Kinzy, Gregers R. Andersen and Roland Beckmann
doi:10.1038/nature05126
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Letters
宇宙：タイタン表面のエタンのスモッグ粒子中への隔離
The sequestration of ethane on Titan in smog particles p669
量子情報科学：単一原子とモノリシック微小共振器の強い結合の観測
Observation of strong coupling between one atom and a monolithic microresonator p671
Takao Aoki, Barak Dayan, E. Wilcut, W. P. Bowen, A. S. Parkins, T. J. Kippenberg, K. J. Vahala and H. J. Kimble
doi:10.1038/nature05147
宇宙：素粒子物理学の標準モデルにより予測した量子色力学転移の次数
The order of the quantum chromodynamics transition predicted by the standard model of particle physics p675
Y. Aoki,
G. Endr
di,
Z. Fodor,
S. D. Katz
and
K. K. Szabó
doi:10.1038/nature05120
日本語要約 | Full Text | PDF (228K)
材料：ナノスケールのキャパシターにおける誘電体デッドレイヤーの起源
Origin of the dielectric dead layer in nanoscale capacitors p679
地球：大気中の酸素の双安定性と大酸化
Bistability of atmospheric oxygen and the Great Oxidation p683
Colin Goldblatt, Timothy M. Lenton and Andrew J. Watson
doi:10.1038/nature05169
進化：哺乳類の種の交代に対する長周期の強力な天文学的強制力
Long-period astronomical forcing of mammal turnover p687
Jan A. van Dam, Hayfaa Abdul Aziz, M. Ángeles Álvarez Sierra, Frederik J. Hilgen, Lars W. van den Hoek Ostende, Lucas J. Lourens, Pierre Mein, Albert J. van der Meulen and Pablo Pelaez-Campomanes
doi:10.1038/nature05163
免疫：絶滅危惧種保全のための小範囲予防接種戦略
Low-coverage vaccination strategies for the conservation of endangered species p692
D. T. Haydon, D. A. Randall, L. Matthews, D. L. Knobel, L. A. Tallents, M. B. Gravenor, S. D. Williams, J. P. Pollinger, S. Cleaveland, M. E. J. Woolhouse, C. Sillero-Zubiri, J. Marino, D. W. Macdonald and M. K. Laurenson
doi:10.1038/nature05177
発生：複眼構造の転換
Transforming the architecture of compound eyes p696
Andrew C. Zelhof, Robert W. Hardy, Ann Becker and Charles S. Zuker
doi:10.1038/nature05128
生理：周皮細胞によるCNSの毛細血管の直径の両方向的な調節
Bidirectional control of CNS capillary diameter by pericytes p700
Claire M. Peppiatt, Clare Howarth, Peter Mobbs and David Attwell
doi:10.1038/nature05193
日本語要約 | Full Text | PDF (1,742K) | Supplementary information
神経：AMPA型グルタミン酸受容体を通るCa流入によって誘発される速い神経伝達物質放出
Fast neurotransmitter release triggered by Ca influx through AMPA-type glutamate receptors p705
Andrés E. Chávez, Joshua H. Singer and Jeffrey S. Diamond
doi:10.1038/nature05123
日本語要約 | Full Text | PDF (1,188K) | Supplementary information
生理：視床下部に局在する食欲抑制分子であるネスファチン-1の発見
Identification of nesfatin-1 as a satiety molecule in the hypothalamus p709
Shinsuke Oh-I, Hiroyuki Shimizu, Tetsurou Satoh, Shuichi Okada, Sachika Adachi, Kinji Inoue, Hiroshi Eguchi, Masanori Yamamoto, Toshihiro Imaki, Koushi Hashimoto, Takafumi Tsuchiya, Tsuyoshi Monden, Kazuhiko Horiguchi, Masanobu Yamada and Masatomo Mori
doi:10.1038/nature05162
遺伝：神経変性疾患の原因タンパク質アプラタキシンは不完全なDNA連結反応中間体を解消する
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates p713
Ivan Ahel, Ulrich Rass, Sherif F. El-Khamisy, Sachin Katyal, Paula M. Clements, Peter J. McKinnon, Keith W. Caldecott and Stephen C. West
doi:10.1038/nature05164
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Addendum
Sustainability of three apple production systems p717
John P. Reganold, Jerry D. Glover, Preston K. Andrews and Herbert R. Hinman
doi:10.1038/nature05188
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Corrigendum
Structure of the E. coli protein-conducting channel bound to a translating ribosome p718
Kakoli Mitra, Christiane Schaffitzel, Tanvir Shaikh, Florence Tama, Simon Jenni, Charles L. Brooks, Nenad Ban and Joachim Frank
doi:10.1038/nature05086
Top of page
Career Views
Naturejobs
ProspectProspects p719
Adaptability can trump planning in career considerations.
Paul Smaglik
doi:10.1038/nj7112-719a
Career Views
King Holmes, director, Department of Global Health, University of Washington, Seattle p720
New public health challenges for King Holmes at the University of Washington.
Virginia Gewin
doi:10.1038/nj7112-720a
More than one route to PhD success p720
Two researchers offer their take on how to succeed as a PhD student.
Sarah Bekessy & Brendan Wintle
doi:10.1038/nj7112-720b
Lab life or love life? p720
Sometimes dedication in the lab leaves little time for personal relationships.
Mhairi Dupré
doi:10.1038/nj7112-720c
