Solving the function of a protein that Dracula may have lacked.
doi:10.1038/7111xiiia
Table of contents
Volume 443 Number 7111 pp481-604
In this issue (5 October 2006)
Also this week
(this content only available online) indicates content that is available online only
Making the paper: John Schuetz pxiii
Abstractions pxiii
doi:10.1038/7111xiiib
Key contribution pxiii
doi:10.1038/7111xiiic
Top of page
Editorials
To build bridges, or to burn them p481
Environmentalists who have grown impatient with science and technology need not be dismissed as beyond the reach of reason.
doi:10.1038/443481a
Power and particles p482
One small step p482
Nature Nanotechnology will spearhead rapid progress in understanding the nanoscale.
doi:10.1038/443482b
Top of page
News
Special ReportClimate in court p486
A forthcoming case in the Supreme Court could push the United States towards regulating against global warming, says Emma Marris.
Emma Marris
doi:10.1038/443486a
Youthful duo snags a swift Nobel for RNA control of genes p488
Award comes just eight years after publication.
Alison Abbott
doi:10.1038/443488a
Sidelines p488
doi:10.1038/443488b
Cosmic ripples net physics prize p489
Vision of early Universe makes its mark.
Katharine Sanderson and Jenny Hogan
doi:10.1038/443489a
Theorists snap over string pieces p491
Q&A: Fabio Mussi p492
Cloners break away from the herd p492
Differentiated cells may hold more promise than adult stem cells.
Helen Pearson
doi:10.1038/443492b
Wikipedia rival calls in the experts p493
Encyclopaedia aims to recognize status of academic editors.
Jim Giles
doi:10.1038/443493a
Top of page
Business
Copycats gear up to dog biotech brands p496
Pressure is mounting on US regulators to create an approval track for generic versions of biotechnology drugs. Meredith Wadman reports.
Meredith Wadman
doi:10.1038/443496a
In brief p497
doi:10.1038/443497a
Market watch p497
Top of page
News Features
Environmental activism: In the name of nature p498
What drives environmental activists to fire-bomb laboratories? Emma Marris investigates a radical fringe of the US green movement.
Emma Marris
doi:10.1038/443498a
Driven to market p502
We're selfish and rational — that's what classical economics says. But play parlour games with brain scanners and you'll find we're pulled in different directions when it comes to money. Jonah Lehrer reports.
Jonah Lehrer
doi:10.1038/443502a
A novel reality p505
Can an advertising executive write an accurate thriller about science? Britta Danger talks to a German author who thinks he has pulled it off.
Britta Danger
doi:10.1038/443505a
Top of page
Correspondence
Speaking different languages on biodiversity p506
Bench-to-bedside solution to funding problems p506
Learning from painful experience of disaster p506
Hoyle's observations were right on the ball p506
Top of page
Books and Arts
Unburdened by proof p507
String theorists are setting a worrying trend by downplaying the need for experimental evidence.
doi:10.1038/443507a
Developing diversity p508
doi:10.1038/443508a
Putting DNA on the map p509
doi:10.1038/443509a
Science in Culture p510
A series of exhibitions across Europe show how Leonardo da Vinci linked art and science.
Stefano Grillo
doi:10.1038/443510a
Top of page
News and Views
微生物学：シャペロンの死
Microbiology: Death of a chaperone p511
To help their growth and spread, bacteria rely on virulence factors, many of which are toxic. One such factor is highly potent, as it attacks a key protein that 'chaperones' other proteins through their synthesis.
Cesare Montecucco and Maurizio Molinari
doi:10.1038/443511a
日本語要約 | Full Text | PDF (421K)
原子物理学：光から原子へ飛び移る量子
Atomic physics: Quantum leap from light to atoms p512
Quantum-information networks use matter for long-term storage and light for long-distance transmission. Teleporting a quantum state from light onto matter has now been achieved.
Mikhail Lukin and Matthew Eisaman
doi:10.1038/443512a
日本語要約 | Full Text | PDF (149K)
細胞周期：複合体の進化
Cell cycle: Complex evolution p513
Cell division is fundamental to life, and so might be expected to have changed little during evolution. Data from four species show that the genes involved can vary, but the regulation of complexes is a common theme.
Gavin Sherlock
doi:10.1038/443513a
日本語要約 | Full Text | PDF (296K)
50 & 100 years ago p513
doi:10.1038/443513b
地球科学：消えたリチウムの発見
Earth Science: Lost lithium found p516
Lithium isotopes provide a fingerprint of recycled material in Earth's upper mantle. But this fingerprint is different from what had been expected. So do we need to reassess our ideas about how the upper mantle evolves?
Elisabeth Widom
doi:10.1038/443516a
日本語要約 | Full Text | PDF (289K)
ナノ技術：SQUIDを小型化する
Nanotechnology: Downsizing SQUIDs p517
微生物学：ばらばらになったゲノムを復活させる
Microbiology: Resurrecting a broken genome p517
A remarkable bacterium can survive extraordinary doses of ionizing radiation that shatter its genome into thousands of pieces. How does it accurately reassemble these DNA fragments into an intact genome?
Susan T. Lovett
doi:10.1038/443517b
日本語要約 | Full Text | PDF (397K)
Correction p519
doi:10.1038/443519a
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News and Views Feature
遺伝学：進化の推進力となるジャンクDNA
Genetics: Junk DNA as an evolutionary force p521
Transposable elements were long dismissed as useless, but they are emerging as major players in evolution. Their interactions with the genome and the environment affect how genes are translated into physical traits.
Christian Biémont and Cristina Vieira
doi:10.1038/443521a
日本語要約 | Full Text | PDF (671K)
Top of page
Top of pageGluconeogenesis: Re-evaluating the FOXO1–PGC-1
Brief Communications
Biomechanics: Robotic whiskers used to sense features p525
Joseph H. Solomon and Mitra J. Hartmann
doi:10.1038/443525a
First paragraph | Full Text | PDF (169K) | Supplementary information
Top of page
Brief Communications Arising
Gluconeogenesis: Re-evaluating the FOXO1–PGC-1
connection pE10
Marcia M. Schilling, James K. Oeser, Jared N. Boustead, Brian P. Flemming and Richard M. O'Brien
doi:10.1038/nature05288
Top of page
Review
生理：in vivo生物学からin silico生物学への往復
From in vivo to in silico biology and back p527
Barbara Di Ventura, Caroline Lemerle, Konstantinos Michalodimitrakis and Luis Serrano
doi:10.1038/nature05127
Top of page
Articles
宇宙：銀河系バルジにあって前面通過を示す太陽系外惑星候補
Transiting extrasolar planetary candidates in the Galactic bulge p534
Kailash C. Sahu, Stefano Casertano, Howard E. Bond, Jeff Valenti, T. Ed Smith, Dante Minniti, Manuela Zoccali, Mario Livio, Nino Panagia, Nikolai Piskunov, Thomas M. Brown, Timothy Brown, Alvio Renzini, R. Michael Rich, Will Clarkson and Stephen Lubow
doi:10.1038/nature05158
日本語要約 | Full Text | PDF (1,791K) | Supplementary information
遺伝：酵母の倍数性に関するゲノム規模の遺伝的解析
Genome-wide genetic analysis of polyploidy in yeast p541
Zuzana Storchová, Amanda Breneman, Jessica Cande, Joshua Dunn, Kendra Burbank, Eileen O'Toole and David Pellman
doi:10.1038/nature05178
生化学：AB5サチラーゼ細胞毒素は小胞体シャペロンBiPを不活性化する
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP p548
Adrienne W. Paton, Travis Beddoe, Cheleste M. Thorpe, James C. Whisstock, Matthew C. J. Wilce, Jamie Rossjohn, Ursula M. Talbot and James C. Paton
doi:10.1038/nature05124
Top of page
Letters
物理：リコネクション時に収縮する磁気アイランドによる電子加速
Electron acceleration from contracting magnetic islands during reconnection p553
J. F. Drake, M. Swisdak, H. Che and M. A. Shay
doi:10.1038/nature05116
量子情報科学：光と物質との間の量子テレポーテーション
Quantum teleportation between light and matter p557
Jacob F. Sherson, Hanna Krauter, Rasmus K. Olsson, Brian Julsgaard, Klemens Hammerer, Ignacio Cirac and Eugene S. Polzik
doi:10.1038/nature05136
海洋：ダンスガード-オシュガー・サイクルを通じた亜熱帯北大西洋における急速な塩分振動
Rapid subtropical North Atlantic salinity oscillations across Dansgaard–Oeschger cycles p561
Matthew W. Schmidt, Maryline J. Vautravers and Howard J. Spero
doi:10.1038/nature05121
日本語要約 | Full Text | PDF (1,252K) | Supplementary information
地球：中央海嶺の玄武岩供給源における沈み込みによって富化したマントルの存在を示唆するリチウム同位体の証拠
Lithium isotope evidence for subduction-enriched mantle in the source of mid-ocean-ridge basalts p565
Tim Elliott, Alex Thomas, Alistair Jeffcoate and Yaoling Niu
doi:10.1038/nature05144
遺伝：Deinococcus radioduransにおける分断された染色体の再構築
Reassembly of shattered chromosomes in Deinococcus radiodurans p569
Ksenija Zahradka, Dea Slade, Adriana Bailone, Suzanne Sommer, Dietrich Averbeck, Mirjana Petranovic, Ariel B. Lindner and Miroslav Radman
doi:10.1038/nature05160
遺伝：多発性硬化症に関連するMHCの共通ハプロタイプの機能的なエピスタシス
Functional epistasis on a common MHC haplotype associated with multiple sclerosis p574
Jon W. Gregersen, Kamil R. Kranc, Xiayi Ke, Pia Svendsen, Lars S. Madsen, Allan Randrup Thomsen, Lon R. Cardon, John I. Bell and Lars Fugger
doi:10.1038/nature05133
医学：1918年に大流行したインフルエンザウイルスによって引き起こされた宿主免疫応答および細胞死応答の増加についてのゲノム解析
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus p578
John C. Kash, Terrence M. Tumpey, Sean C. Proll, Victoria Carter, Olivia Perwitasari, Matthew J. Thomas, Christopher F. Basler, Peter Palese, Jeffery K. Taubenberger, Adolfo García-Sastre, David E. Swayne and Michael G. Katze
doi:10.1038/nature05181
細胞：細胞内のマラリア原虫による、ナトリウムに依存した無機リン酸の取り込み
Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite p582
Kevin J. Saliba, Rowena E. Martin, Angelika Bröer, Roselani I. Henry, C. Siobhan McCarthy, Megan J. Downie, Richard J. W. Allen, Kylie A. Mullin, Geoffrey I. McFadden, Stefan Bröer and Kiaran Kirk
doi:10.1038/nature05149
細胞：哺乳類ミトコンドリアのポルフィリン輸送体の同定
Identification of a mammalian mitochondrial porphyrin transporter p586
Partha C. Krishnamurthy, Guoqing Du, Yu Fukuda, Daxi Sun, Janardhan Sampath, Kelly E. Mercer, Junfeng Wang, Beatriz Sosa-Pineda, K. Gopal Murti and John D. Schuetz
doi:10.1038/nature05125
生化学：DDB1-CUL4Aユビキチンリガーゼ複合体の分子構造と会合機構
Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery p590
Stephane Angers, Ti Li, Xianhua Yi, Michael J. MacCoss, Randall T. Moon and Ning Zheng
doi:10.1038/nature05175
進化：細胞周期に応じた転写調節と翻訳後調節の共進化
Co-evolution of transcriptional and post-translational cell-cycle regulation p594
Lars Juhl Jensen, Thomas Skøt Jensen, Ulrik de Lichtenberg, Søren Brunak and Peer Bork
doi:10.1038/nature05186
Top of page
Corrigenda
Sexual reproduction selects for robustness and negative epistasis in artificial gene networks p598
Ricardo B. R. Azevedo, Rolf Lohaus, Suraj Srinivasan, Kristen K. Dang and Christina L. Burch
doi:10.1038/nature05189
Arctic hydrology during global warming at the Palaeocene/Eocene thermal maximum p598
Mark Pagani, Nikolai Pedentchouk, Matthew Huber, Appy Sluijs, Stefan Schouten, Henk Brinkhuis, Jaap S. Sinninghe Damsté, Gerald R. Dickens & the Expedition 302 test Scientists and , (Jan Backman, Steve Clemens, Thomas Cronin, Frédérique Eynaud, Jérôme Gattacceca, Martin Jakobsson, Ric Jordan, Michael Kaminski, John King, Nalân Koc, Nahysa C. Martinez, Jens Matthiessen, David McInroy, Theodore C. Moore, Jr, Kathryn Moran, Matthew O'Regan, Jonaotaro Onodera, Heiko Pälike, Brice Rea, Domenico Rio, Tatsuhiko Sakamoto, David C. Smith, Ruediger Stein, Kristen E. K. St John, Itsuki Suto, Noritoshi Suzuki, Kozo Takahashi, Mahito Watanabe and Masanobu Yamamoto)
doi:10.1038/nature05211
Top of page
Special Report
Career Views
Highlights
Naturejobs
ProspectProspects p599
Paul Smaglik
doi:10.1038/nj7111-599a
Special Report
A jumping off point p600
The recent flood of genome sequences has given evolutionary genetics a boost. Ricki Lewis takes a sharp look at a varied field.
Ricki Lewis
doi:10.1038/nj7111-600a
Career Views
Sam Aronson, director, Brookhaven National Laboratory, Upton, New York p602
Sam Aronson takes the helm at Brookhaven.
Virginia Gewin
doi:10.1038/nj7111-602a
Stand up and be quoted p602
Society of young UK scientists fosters better interaction with media.
Richard Van Noorden
doi:10.1038/nj7111-602b
D-day p602
After years of preparation, dissertation day looms large.
Andreas Andersson
doi:10.1038/nj7111-602c
Highlights
Highlight: The National Institutes of Health
doi:10.1038/nj0126
