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Evolution

Different paths to the same end

Genetic dissection of a yeast gene-regulatory pathway shows that the logical output of such a pathway can remain the same even though the molecular mechanisms underlying the output have diverged remarkably.

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Figure 1: The divergent regulatory architectures associated with yeast mating type.

References

  1. Carroll, S. B. PLoS Biol. 3, e245 (2005).

    Article  Google Scholar 

  2. Tsong, A. E., Tuch, B. B., Li, H. & Johnson, A. D. Nature 443, 415–420 (2006).

    Article  ADS  CAS  Google Scholar 

  3. Acton, T. B., Mead, J., Steiner, A. M. & Vershon, A. K. Mol. Cell. Biol. 20, 1–11 (2000).

    Article  CAS  Google Scholar 

  4. True, J. R. & Haag, E. S. Evol. Dev. 3, 109–119 (2001).

    Article  CAS  Google Scholar 

  5. Weiss, K. M. & Fullerton, S. M. Theor. Popul. Biol. 57, 187–195 (2000).

    Article  CAS  Google Scholar 

  6. Acton, T. B., Zhong, H. & Vershon, A. K. Mol. Cell. Biol. 17, 1881–1889 (1997).

    Article  CAS  Google Scholar 

  7. Tsong, A. E., Miller, M. G., Raisner, R. M. & Johnson, A. D. Cell 115, 389–399 (2003).

    Article  CAS  Google Scholar 

  8. Tanay, A., Regev, A. & Shamir, R. Proc. Natl Acad. Sci. USA 102, 7203–7208 (2005).

    Article  ADS  CAS  Google Scholar 

  9. Kawasaki, K., Suzuki, T. & Weiss, K. M. Proc. Natl Acad. Sci. USA 102, 18063–18068 (2005).

    Article  ADS  CAS  Google Scholar 

  10. Ludwig, M. Z., Bergman, C., Patel, N. H. & Kreitman, M. Nature 403, 564–567 (2000).

    Article  ADS  CAS  Google Scholar 

  11. Butler, G. et al. Proc. Natl Acad. Sci. USA 101, 1632–1637 (2004).

    Article  ADS  CAS  Google Scholar 

  12. Logue, M. E., Wong, S., Wolfe, K. H. & Butler, G. Eukaryot. Cell 4, 1009–1017 (2005).

    Article  CAS  Google Scholar 

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Rokas, A. Different paths to the same end. Nature 443, 401–402 (2006). https://doi.org/10.1038/443401a

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