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Nature 443, 401-402 (28 September 2006) | doi:10.1038/443401a; Published online 27 September 2006
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Professor of Cognitive Neuroscience
- Karolinska Institute
- Stockholm Sweden
University Full-Professor (W3, Tenure Track)
- University of Münster
- Munster 48149 Germany
Evolution: Different paths to the same end
Antonis Rokas
Abstract
Genetic dissection of a yeast gene-regulatory pathway shows that the logical output of such a pathway can remain the same even though the molecular mechanisms underlying the output have diverged remarkably.
From penguins to mushrooms and baobabs, the world around us harbours a bewildering diversity of life forms. Much of the evolution of this diversity is due to changes in the under-lying genetic regulatory architecture1.
- Antonis Rokas is in the Microbial Genome Analysis and Annotation Group, The Broad Institute of MIT and Harvard, 7 Cambridge Center, Massachusetts 02142, USA.
Email: arokas@mit.edu
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Evolution of alternative transcriptional circuits with identical logicNature Article (28 Sep 2006)
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