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Nature 443, 282-283 (21 September 2006) | doi:10.1038/443282a; Published online 20 September 2006
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Canada Research Chair (Tier 1) Alfred Bader Chair in Organic Chemistry
- Queens University
- Kingston, ON, Canada
Gastroenterologist
- Gastrointestinal Diseases Inc.
- Georgia, USA
HIV: Tired T cells turn around
Sarah Rowland-Jones1 & Tao Dong1
Abstract
HIV-1 prompts a massive cellular immune response, but eventually it tires the immune cells. Blocking the activation of a cell receptor called PD-1 might restore these exhausted cells.
"There are only the pursued, the pursuing, the busy, and the tired."F.
- Sarah Rowland-Jones and Tao Dong are in the MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford OX3 9DS, UK. Sarah Rowland-Jones is also at the MRC Laboratories, Fajara, Gambia.
Email: sarah.rowland-jones@ndm.ox.ac.uk
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