Figures and Tables

From the following article:

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism

Satoshi Murakami, Ryosuke Nakashima, Eiki Yamashita, Takashi Matsumoto and Akihito Yamaguchi

Nature 443, 173-179(14 September 2006)

doi:10.1038/nature05076

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Structure of the AcrB–minocycline complex based on the asymmetric crystal.

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Figure 2

Multidrug recognition by AcrB.

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Figure 3

The novel drug translocation pathway for AcrB.

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Figure 4

Structure with a slab (approx23 Å) of the transmembrane domain viewed from the periplasmic side.

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Figure 5

Schematic illustration of the proposed 'functionally rotating ordered multidrug binding change mechanism' mediated by AcrB.

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