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Nature 443, 40-41 (7 September 2006) | doi:10.1038/443040b; Published online 6 September 2006

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Organic chemistry: Catalysts break symmetry

Scott E. Denmark1

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The creation of asymmetric molecules from symmetrical precursors is a useful strategy for organic synthesis. A new catalyst can accomplish this task through a unique, symmetry-breaking reaction.

Chirality, the 'left-handed' or 'right-handed' property of objects that are mirror images of each other, is ubiquitous in the observable world — shoes, conch shells, wood screws and umbilical cords, for instance. This property extends to objects in the nanoscale dimension; nearly all molecules in nature (such as amino acids, sugars, alkaloids and terpenes) and legions of synthetic compounds are chiral.

  1. Scott E. Denmark is in the Department of Chemistry, University of Illinois, 600 S. Mathews Avenue, Urbana, Illinois 61801, USA.
    Email: denmark@scs.uiuc.edu

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