Table of contents
Volume 442 Number 7105 pp847-956
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Editorials
After Toronto p847
Effective AIDS prevention requires far better understanding of why existing strategies do not succeed.
doi:10.1038/442847a
State of readiness p847
The anniversary of Hurricane Katrina should remind scientists to keep disaster recovery plans in order.
doi:10.1038/442847b
Foo's paradise p848
In praise of chat.
doi:10.1038/442848a
News
Light shed on battle against HIV p852
Simple strategy may give embattled cells a boost.
Erika Check
doi:10.1038/442852a
China set to make fusion history p853
Plasma physics comes under scrutiny in new breed of tokamak.
Ichiko Fuyuno
doi:10.1038/442853a
Oceans cool off in hottest years p854
Temperature drop puzzles climate researchers.
Quirin Schiermeier
doi:10.1038/442854a
Asteroid fly-by eludes study p855
Astronomers rue the one that got away.
Heidi Ledford
doi:10.1038/442855a
What happens after the water recedes? p856
New Orleans universities are still struggling to recover from the ravages of Hurricane Katrina. Heidi Ledford examines how researchers at one leading institution are coping.
doi:10.1038/442856a
Sidelines p858
doi:10.1038/442858a
Early embryos can yield stem cells... and survive p858
Could extraction technique resolve ethical problems?
Helen Pearson
doi:10.1038/442858b
Business
Getting the right mix p860
Biotechnology companies come in many shapes and sizes, but, say two economists, the ones with the widest spread of skills in their teams stand the best chances of success. Aaron Bouchie reports.
doi:10.1038/442860a
In brief p861
doi:10.1038/442861a
Market watch p861
Colin Macilwain
doi:10.1038/442861b
News Features
Appropriate technology: Make anything, anywhere p862
Can everyone use technology creatively? Engineers at the Massachusetts Institute of Technology think so and have launched 'Fab Labs' around the world to prove it. Apoorva Mandavilli reports.
doi:10.1038/442862a
Neurodevelopment: How does the teenage brain work? p865
Changes in the structure of children's brains may account for some of the risky business of adolescence, Kendall Powell finds.
doi:10.1038/442865a
See also: Editor's summary
Correspondence
Gender: missing the prizes that can inspire a career p868
Annette C. Dolphin
doi:10.1038/442868a
See also: Editor's summary
Gender: macho language and other deterrents p868
Molly Carnes
doi:10.1038/442868b
See also: Editor's summary
A positive definition of prokaryotes p868
William Martin and Eugene V. Koonin
doi:10.1038/442868c
Books and Arts
Solving an age-old problem p869
Western governments need to rethink their approach to dealing with an ageing population.
John Grimley Evans reviews The Denial of Aging by Muriel R. Gillick
doi:10.1038/442869a
A walk in a quantum world p870
Michael Berry reviews Fantastic Realities: 49 Mind Journeys and a Trip to Stockholm by Frank Wilczek
doi:10.1038/442870a
From mysticism to medicine p871
doi:10.1038/442871a
A blast from the past p871
Sandra Knapp reviews The Science of Describing: Natural History in Renaissance Europe by Brian W. Ogilvie
doi:10.1038/442871b
News and Views
Earth Sciences: Signature required p873
Most geologists agree that Earth's atmosphere was oxygen-free until 2.4 billion years ago. But the latest sulphur-isotope measurements from sedimentary rocks suggest otherwise.
L. Paul Knauth
doi:10.1038/442873a
See also: Editor's summary
Cell biology: A licence for duplication p874
Genome stability in animal cells requires strict control over the numbers of the organelles called centrosomes. An attractive 'licensing' model now explains how centrosome duplication is restricted to just once per cell cycle.
Erich A. Nigg
doi:10.1038/442874a
See also: Editor's summary
50 & 100 years ago p875
doi:10.1038/442875a
Nuclear physics: Island ahoy! p876
Measurements of the energy levels of unstable superheavy nuclei are beginning to afford distant vistas of a promised land — 'the island of stability' beyond the bounds of the conventional periodic table.
Mark A. Stoyer
doi:10.1038/442876a
See also: Editor's summary
Biochemistry: Mussel muscle p877
Andrew Mitchinson
doi:10.1038/442877b
Physiology: Nitrate at the ion exchange p877
The distinction between CLC ion channels and ion exchangers has become blurred. The physiological role of CLC exchangers has been a mystery, but one function is evidently to concentrate nitrate in plant vacuoles.
Julian I. Schroeder
doi:10.1038/nature04999
Solid-state-chemistry: Framework for a molecular prison p878
A remarkable family of solids exists in which host compounds hold guest molecules captive in their rooms. The latest example has an unprecedented topology and opens up fresh avenues for investigation.
Michel Pouchard
doi:10.1038/442878a
Brief Communications
Social evolution: Kin preference in a social microbe p881
Given the right circumstances, even an amoeba chooses to be altruistic towards its relatives.
Natasha J. Mehdiabadi, Chandra N. Jack, Tiffany Talley Farnham, Thomas G. Platt, Sara E. Kalla, Gad Shaulsky, David C. Queller and Joan E. Strassmann
doi:10.1038/442881a
First paragraph | Full Text | PDF (286K) | Supplementary information
See also: Editor's summary
Gene expression: Long-term gene silencing by RNAi p882
Nadine L. Vastenhouw, Karin Brunschwig, Kristy L. Okihara, Fritz Müller, Marcel Tijsterman and Ronald H. A. Plasterk
doi:10.1038/442882a
First paragraph | Full Text | PDF (179K) | Supplementary information
See also: Editor's summary
Top of page
Brief Communications Arising
Protein evolution: Causes of trends in amino-acid gain and loss pE11
Laurence D. Hurst, Edward J. Feil and Eduardo P. C. Rocha
doi:10.1038/nature05137
First paragraph | Full Text | PDF (152K)
Protein evolution: Causes of trends in amino-acid gain and loss (Reply) pE12
I. K. Jordan, F. A. Kondrashov, I. A. Adzhubei, Y. I. Wolf, E. V. Koonin, A. S. Kondrashov and S. Sunyaev
doi:10.1038/nature05138
First paragraph | Full Text | PDF (152K)
Article
RecA acts in trans to allow replication of damaged DNA by DNA polymerase V p883
Katharina Schlacher, Michael M. Cox, Roger Woodgate and Myron F. Goodman
doi:10.1038/nature05042
Abstract | Full Text | PDF (562K) | Supplementary information
See also: Editor's summary
Letters
Suppression of star formation in early-type galaxies by feedback from supermassive black holes p888
Kevin Schawinski, Sadegh Khochfar, Sugata Kaviraj, Sukyoung K. Yi, Alessandro Boselli, Tom Barlow, Tim Conrow, Karl Forster, Peter G. Friedman, D. Chris Martin, Patrick Morrissey, Susan Neff, David Schiminovich, Mark Seibert, Todd Small, Ted K. Wyder, Luciana Bianchi, Jose Donas, Tim Heckman, Young-Wook Lee, Barry Madore, Bruno Milliard, R. Michael Rich and Alex Szalay
doi:10.1038/nature04934
First paragraph | Full Text | PDF (3,461K) | Supplementary information
See also: Editor's summary
Transient pulsed radio emission from a magnetar p892
Fernando Camilo, Scott M. Ransom, Jules P. Halpern, John Reynolds, David J. Helfand, Neil Zimmerman and John Sarkissian
doi:10.1038/nature04986
First paragraph | Full Text | PDF (471K)
See also: Editor's summary
Nuclear isomers in superheavy elements as stepping stones towards the island of stability p896
R.-D. Herzberg, P. T. Greenlees, P. A. Butler, G. D. Jones, M. Venhart, I. G. Darby, S. Eeckhaudt, K. Eskola, T. Grahn, C. Gray-Jones, F. P. Hessberger, P. Jones, R. Julin, S. Juutinen, S. Ketelhut, W. Korten, M. Leino, A.-P. Leppänen, S. Moon, M. Nyman, R. D. Page, J. Pakarinen, A. Pritchard, P. Rahkila, J. Sarén, C. Scholey, A. Steer, Y. Sun, Ch. Theisen and J. Uusitalo
doi:10.1038/nature05069
First paragraph | Full Text | PDF (314K)
See also: Editor's summary | News and Views by Stoyer
Magnetic impurity formation in quantum point contacts p900
Toma
Rejec
and
Yigal Meir
doi:10.1038/nature05054
First paragraph | Full Text | PDF (340K)
Dependence of single-molecule junction conductance on molecular conformation p904
Latha Venkataraman, Jennifer E. Klare, Colin Nuckolls, Mark S. Hybertsen and Michael L. Steigerwald
doi:10.1038/nature05037
First paragraph | Full Text | PDF (619K) | Supplementary information
Sulphur isotope evidence for an oxic Archaean atmosphere p908
Hiroshi Ohmoto, Yumiko Watanabe, Hiroaki Ikemi, Simon R. Poulson and Bruce E. Taylor
doi:10.1038/nature05044
First paragraph | Full Text | PDF (381K) | Supplementary information
See also: Editor's summary
Parochial altruism in humans p912
Helen Bernhard, Urs Fischbacher and Ernst Fehr
doi:10.1038/nature04981
First paragraph | Full Text | PDF (209K) | Supplementary information
See also: Editor's summary
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 p916
Matt Baker, Ian R. Mackenzie, Stuart M. Pickering-Brown, Jennifer Gass, Rosa Rademakers, Caroline Lindholm, Julie Snowden, Jennifer Adamson, A. Dessa Sadovnick, Sara Rollinson, Ashley Cannon, Emily Dwosh, David Neary, Stacey Melquist, Anna Richardson, Dennis Dickson, Zdenek Berger, Jason Eriksen, Todd Robinson, Cynthia Zehr, Chad A. Dickey, Richard Crook, Eileen McGowan, David Mann, Bradley Boeve, Howard Feldman and Mike Hutton
doi:10.1038/nature05016
First paragraph | Full Text | PDF (379K) | Supplementary information
See also: Editor's summary
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 p920
Marc Cruts, Ilse Gijselinck, Julie van der Zee, Sebastiaan Engelborghs, Hans Wils, Daniel Pirici, Rosa Rademakers, Rik Vandenberghe, Bart Dermaut, Jean-Jacques Martin, Cornelia van Duijn, Karin Peeters, Raf Sciot, Patrick Santens, Tim De Pooter, Maria Mattheijssens, Marleen Van den Broeck, Ivy Cuijt, Krist'l Vennekens, Peter P. De Deyn, Samir Kumar-Singh and Christine Van Broeckhoven
doi:10.1038/nature05017
First paragraph | Full Text | PDF (366K) | Supplementary information
See also: Editor's summary
Highly ordered arrangement of single neurons in orientation pinwheels p925
Kenichi Ohki, Sooyoung Chung, Prakash Kara, Mark Hübener, Tobias Bonhoeffer and R. Clay Reid
doi:10.1038/nature05019
First paragraph | Full Text | PDF (534K) | Supplementary information
NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus p929
Ayumu Tashiro, Vladislav M. Sandler, Nicolas Toni, Chunmei Zhao and Fred H. Gage
doi:10.1038/nature05028
First paragraph | Full Text | PDF (1,314K) | Supplementary information
See also: Editor's summary
The cells and logic for mammalian sour taste detection p934
Angela L. Huang, Xiaoke Chen, Mark A. Hoon, Jayaram Chandrashekar, Wei Guo, Dimitri Tränkner, Nicholas J. P. Ryba and Charles S. Zuker
doi:10.1038/nature05084
First paragraph | Full Text | PDF (506K) | Supplementary information
See also: Editor's summary
The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles p939
A. De Angeli, D. Monachello, G. Ephritikhine, J. M. Frachisse, S. Thomine, F. Gambale and H. Barbier-Brygoo
doi:10.1038/nature05013
First paragraph | Full Text | PDF (325K) | Supplementary information
See also: News and Views by Schroeder
Signal sequence directs localized secretion of bacterial surface proteins p943
Fredric Carlsson, Margaretha Stålhammar-Carlemalm, Klas Flärdh, Charlotta Sandin, Eric Carlemalm and Gunnar Lindahl
doi:10.1038/nature05021
First paragraph | Full Text | PDF (398K) | Supplementary information
Mechanism limiting centrosome duplication to once per cell cycle p947
Meng-Fu Bryan Tsou and Tim Stearns
doi:10.1038/nature04985
First paragraph | Full Text | PDF (538K) | Supplementary information
See also: Editor's summary | News and Views by Nigg
Naturejobs
ProspectProspects p953
US universities are working hard to boost enrolments from foreign graduate students.
Paul Smaglik
doi:10.1038/nj7105-953a