Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 442, 750-752 (17 August 2006) | doi:10.1038/442750a; Published online 16 August 2006
Open Innovation Challenges
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
- More Challenges
- Powered by:
nature jobs
Paleobiologist / Biogeochemist
- University of Cincinnati
- Cincinnati, Ohio, USA
Instrumentation Engineer
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Genomics: Predictable packaging
Timothy J. Richmond1
Abstract
Nuclear factors must access specific sites within genomic DNA to function, yet the DNA is bundled up into many nucleosomes. Is the DNA sequence sufficiently informative to predict where each nucleosome will be?
The genomes of eukaryotic organisms — plants, fungi and animals — range in length from 10 million to 100 billion base pairs. All of this DNA is packaged into a structure known as chromatin so that it can fit into the cell nucleus, which is only a few micrometres in diameter.
- Timothy J. Richmond is at the ETH Zürich, Institut für Molekularbiologie und Biophysik, Schafmattstrasse 20, 8093 Zürich, Switzerland.
Email: richmond@mol.biol.ethz.ch
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
New evidence that DNA encodes its packagingNature Genetics News and Views (01 Oct 2006)
A milestone in the odyssey of higher-order chromatin structureNature Structural & Molecular Biology News and Views (01 Aug 2005)
See all 5 matches for News And ViewsRESEARCH
The structure of DNA in the nucleosome coreNature Article (08 May 2003)
Nucleosomes can invade DNA territories occupied by their neighborsNature Structural & Molecular Biology Article (01 Feb 2009)
See all 19 matches for Research