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Nature 442, 637-638 (10 August 2006) | doi:10.1038/nature05001; Published online 30 July 2006

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Neuroscience: An extra dimension to olfaction

John Ngai1

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The sense of smell is triggered by receptors in the olfactory epithelium that lines the nose. In mice at least, that lining is also responsible for receiving chemosensory cues involved in mating and other social behaviours.

In 1991, Linda Buck and Richard Axel reported the seminal discovery of the gene family that encodes odorant receptors in vertebrates1. A paper by Buck and Stephen Liberles2 on page 645 of this issue describes a second class of chemosensory receptor expressed by olfactory sensory neurons.

  1. John Ngai is in the Department of Molecular and Cell Biology, and the Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720, USA.
    Email: jngai@socrates.berkeley.edu

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