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Editorials

Safeguards for donors p601

Clashing perspectives on the ethics of the donation of human eggs for research purposes are likely to complicate international collaboration — whether stem-cell researchers like it or not.

doi:10.1038/442601a


Capturing carbon p601

Sequestration of greenhouse gases could play an important role in capping emissions.

doi:10.1038/442601b


Toronto crossroads p602

The international AIDS meeting still has a purpose.

doi:10.1038/442602a


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Research Highlights

Research highlights p604

doi:10.1038/442604a


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News

Special Report

Ethicists and biologists ponder the price of eggs p606

A Nature Special Report investigates the ethics and economics of donating eggs for stem-cell research. In this, the first part Erika Check investigates whether paying donors would increase supply. In the second part Helen Pearson asks what is known about the long-term health risks faced by donors.

Erika Check

doi:10.1038/442606a


Health effects of egg donation may take decades to emerge p607

A Nature Special Report investigates the ethics and economics of donating eggs for stem-cell research. In the first part Erika Check investigated whether paying donors would increase supply. In this, the second part Helen Pearson asks what is known about the long-term health risks faced by donors.

Helen Pearson

doi:10.1038/442607a


Oil from bombed plant left to spill p609

War hampers clean-up efforts.

Kerri Smith with additional reporting by Michael Hopkin

doi:10.1038/442609a


Plan for postdoc union sparks backlash p609

University of California awaits petition ruling.

Heidi Ledford

doi:10.1038/442609b


AIDS vaccine research becomes 'big science' p610

But 'mission-oriented' approach has its critics.

Declan Butler

doi:10.1038/442610a

See also: Editor's summary


Sidelines p611

doi:10.1038/442611a


Views collide over fate of accelerator p612

Decommissioned particle smasher awaits fate.

Geoff Brumfiel

doi:10.1038/442612a


News in brief p613

doi:10.1038/442613a


Correction p613

doi:10.1038/442613b


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Business

Silent running: the race to the clinic p614

A technique for turning genes off has sparked a flurry of biotech investment. Erika Check investigates.

doi:10.1038/442614a


In brief p615

doi:10.1038/442615a


Market watch p615

Quirin Schiermeier

doi:10.1038/442615b


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News Features

AIDS treatment: Staying the course p617

Some feared that widespread use of AIDS treatments in Africa would encourage drug resistance, with globally disastrous consequences. But there's no crisis yet, reports Erika Check.

doi:10.1038/442617a

See also: Editor's summary


Putting the carbon back: The hundred billion tonne challenge p620

One way to keep carbon dioxide out of the atmosphere is to put it back in the ground. In this, the first of two News Features on carbon sequestration, Quirin Schiermeier asks when the world's coal-fired power plants will start storing away their carbon. In the second, Emma Marris joins the enthusiasts who think that enriching Earth's soils with charcoal can help avert global warming, reduce the need for fertilizers, and greatly increase the size of turnips.

doi:10.1038/442620a

See also: Editor's summary


Putting the carbon back: Black is the new green p624

One way to keep carbon dioxide out of the atmosphere is to put it back in the ground. In the first of two News Features on carbon sequestration, Quirin Schiermeier asked when the world's coal-fired power plants will start storing away their carbon. In the second, Emma Marris joins the enthusiasts who think that enriching Earth's soils with charcoal can help avert global warming, reduce the need for fertilizers, and greatly increase the size of turnips.

doi:10.1038/442624a

See also: Editor's summary


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Correspondence

Scientists are well placed to speak up for biodiversity p627

Guillaume Chapron

doi:10.1038/442627a


Authors were clear about hockey-stick uncertainties p627

Raymond S. Bradley, Malcolm K. Hughes & Michael E. Mann

doi:10.1038/442627b


Systems biology could help us harness useful microbes p627

Douglas Young

doi:10.1038/442627c


Sticking points in the push for change p627

Eugene A. Rosa

doi:10.1038/442627d


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Commentary

Fair payment or undue inducement? p629

Women who donate their eggs for stem-cell research should be compensated in the same way as other healthy research volunteers, argues Insoo Hyun.

doi:10.1038/442629a

See also: Editor's summary


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Books and Arts

The Moses of Silicon Valley p631

William Shockley's work led to the foundation of the US computer industry.

Paul Grant reviews Broken Genius: The Rise and Fall of William Shockley, Creator of the Electronic Age by Joel N. Shurkin

doi:10.1038/442631a


New in paperback p632

doi:10.1038/442632a


Making sense of autism p632

Francesca Happé reviews Autism, Brain, and Environment by Richard Lathe and Understanding Autism: From Basic Neuroscience to Treatment edited by Steven O. Moldin & John L. R. Rubenstein

doi:10.1038/442632b


Subterranean storage blues p633

Gordon MacKerron reviews Uncertainty Underground: Yucca Mountain and the Nation's High-Level Nuclear Waste edited by Allison M. Macfarlane & Rodney C. Ewing

doi:10.1038/442633a

See also: Editor's summary


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News and Views

Plant breeding: Rice in deep water p635

Many otherwise productive cultivars of rice suffer badly if immersed in water for long. The identification of a gene variant that confers tolerance to this threat has practical potential.

Takuji Sasaki

doi:10.1038/442635a

See also: Editor's summary


Cosmology: Where all the lithium went p636

For some years, astronomers have been trying to track down all the lithium predicted by standard cosmological models. Spectroscopic dissection of globular clusters reveals that the answer might lie in the stars.

Corinne Charbonnel

doi:10.1038/442636a

See also: Editor's summary


Neuroscience: An extra dimension to olfaction p637

The sense of smell is triggered by receptors in the olfactory epithelium that lines the nose. In mice at least, that lining is also responsible for receiving chemosensory cues involved in mating and other social behaviours.

John Ngai

doi:10.1038/nature05001

See also: Editor's summary


Materials science: Organosilica the conciliator p638

Acidic and basic molecules are antagonistic, and keeping them in their place is no easy job — unless, it seems, one unites them under the tutelage of ordered, nanoporous materials known as organosilicas.

Mietek Jaroniec

doi:10.1038/442638a


Solar System: Sifting through the debris p640

A quadrillion previously unnoticed small bodies beyond Neptune have been spotted as they dimmed X-rays from a distant source. Models of the dynamics of debris in the Solar System's suburbs must now be reworked.

Asantha Cooray

doi:10.1038/442640a

See also: Editor's summary


Neurodegenerative disease: Cut to the chase p641

A family of enzymes called caspases — best known for their involvement in programmed cell death — now seems to be pivotal in the progression of two neurodegenerative diseases.

Lisa M. Ellerby & Harry T. Orr

doi:10.1038/442641a


50 & 100 years ago p642

doi:10.1038/442642a


Microscopy: Nanotomography comes of age p642

The use of X-rays to construct three-dimensional tomographic images is well established in medicine. The same principle is being extended to the nanoscale, bringing us startlingly accurate pictures of tiny objects.

David Attwood

doi:10.1038/442642b


Neuroscience: Making faces in the brain p644

Artificially activating the right neurons at the right time causes visual perception of a face. This new result shows that such neurons directly underlie the recognition of complex objects.

James J. DiCarlo

doi:10.1038/nature05000

See also: Editor's summary


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Articles

A second class of chemosensory receptors in the olfactory epithelium p645

Stephen D. Liberles & Linda B. Buck

doi:10.1038/nature05066

See also: Editor's summary | News and Views by Ngai


Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity p651

Olaf Gross, Andreas Gewies, Katrin Finger, Martin Schäfer, Tim Sparwasser, Christian Peschel, Irmgard Förster & Jürgen Ruland

doi:10.1038/nature04926

See also: Editor's summary


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Letters

A probable stellar solution to the cosmological lithium discrepancy p657

A. J. Korn, F. Grundahl, O. Richard, P. S. Barklem, L. Mashonkina, R. Collet, N. Piskunov & B. Gustafsson

doi:10.1038/nature05011

See also: Editor's summary


Occultation of X-rays from Scorpius X-1 by small trans-neptunian objects p660

Hsiang-Kuang Chang, Sun-Kun King, Jau-Shian Liang, Ping-Shien Wu, Lupin Chun-Che Lin & Jeng-Lun Chiu

doi:10.1038/nature04941

See also: Editor's summary


Tracking the motion of charges in a terahertz light field by femtosecond X-ray diffraction p664

A. Cavalleri, S. Wall, C. Simpson, E. Statz, D. W. Ward, K. A. Nelson, M. Rini & R. W. Schoenlein

doi:10.1038/nature05041

See also: Editor's summary


Supercurrent reversal in quantum dots p667

Jorden A. van Dam, Yuli V. Nazarov, Erik P. A. M. Bakkers, Silvano De Franceschi & Leo P. Kouwenhoven

doi:10.1038/nature05018


Arctic hydrology during global warming at the Palaeocene/Eocene thermal maximum p671

Mark Pagani, Nikolai Pedentchouk, Matthew Huber, Appy Sluijs, Stefan Schouten, Henk Brinkhuis, Jaap S. Sinninghe Damsté, Gerald R. Dickens & Expedition 302 ScientistsExpedition 302 ScientistsJan Backman, Steve Clemens, Thomas Cronin, Frédérique Eynaud, Jérôme Gattacceca, Martin Jakobsson, Ric Jordan, Michael Kaminski, John King, Nalân Koc, Nahysa C. Martinez, David McInroy, Theodore C. Moore Jr, Matthew O'Regan, Jonaotaro Onodera, Heiko Pälike, Brice Rea, Domenico Rio, Tatsuhiko Sakamoto, David C. Smith, Kristen E. K. St John, Itsuki Suto, Noritoshi Suzuki, Kozo Takahashi, Mahito Watanabe & Masanobu Yamamoto

doi:10.1038/nature05043

See also: Corrigendum by Pagani et al.


The dynamics of melt and shear localization in partially molten aggregates p676

Richard F. Katz, Marc Spiegelman & Benjamin Holtzman

doi:10.1038/nature05039

See also: Editor's summary


Synchrotron X-ray tomographic microscopy of fossil embryos p680

Philip C. J. Donoghue, Stefan Bengtson, Xi-ping Dong, Neil J. Gostling, Therese Huldtgren, John A. Cunningham, Chongyu Yin, Zhao Yue, Fan Peng & Marco Stampanoni

doi:10.1038/nature04890

See also: Editor's summary


Minimal ProtoHox cluster inferred from bilaterian and cnidarian Hox complements p684

D. Chourrout, F. Delsuc, P. Chourrout, R. B. Edvardsen, F. Rentzsch, E. Renfer, M. F. Jensen, B. Zhu, P. de Jong, R. E. Steele & U. Technau

doi:10.1038/nature04863

See also: Editor's summary


Mesodermal Wnt2b signalling positively regulates liver specification p688

Elke A. Ober, Heather Verkade, Holly A. Field & Didier Y. R. Stainier

doi:10.1038/nature04888


Microstimulation of inferotemporal cortex influences face categorization p692

Seyed-Reza Afraz, Roozbeh Kiani & Hossein Esteky

doi:10.1038/nature04982

See also: Editor's summary | News and Views by DiCarloCorrigendum by Afraz et al.


Enzymatic activation of voltage-gated potassium channels p696

Yajamana Ramu, Yanping Xu & Zhe Lu

doi:10.1038/nature04880


An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis p700

Fajun Yang, Bryan W. Vought, John S. Satterlee, Amy K. Walker, Z.-Y. Jim Sun, Jennifer L. Watts, Rosalie DeBeaumont, R. Mako Saito, Sven G. Hyberts, Shaosong Yang, Christine Macol, Lakshmanan Iyer, Robert Tjian, Sander van den Heuvel, Anne C. Hart, Gerhard Wagner & Anders M. Näär

doi:10.1038/nature04942


Sub1A is an ethylene-response-factor-like gene that confers submergence tolerance to rice p705

Kenong Xu, Xia Xu, Takeshi Fukao, Patrick Canlas, Reycel Maghirang-Rodriguez, Sigrid Heuer, Abdelbagi M. Ismail, Julia Bailey-Serres, Pamela C. Ronald & David J. Mackill

doi:10.1038/nature04920

See also: Editor's summary


Assembly dynamics of microtubules at molecular resolution p709

Jacob W. J. Kerssemakers, E. Laura Munteanu, Liedewij Laan, Tim L. Noetzel, Marcel E. Janson & Marileen Dogterom

doi:10.1038/nature04928


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Naturejobs

Prospect

Prospects p713

Postdoc is caught up in Israeli-Hezbollah conflict.

Paul Smaglik

doi:10.1038/nj7102-713a


Region

Japan's other research hub p714

The city of Sendai has much to offer research and industry, but, says David Cyranoski, competition for funding and brains is stiff.

David Cyranoski

doi:10.1038/nj7103-714a


Spotlight

Spotlight on Sendai

doi:10.1038/nj0122


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Futures

Statler pulchrifex p718

Make love and war.

Matt Weber

doi:10.1038/442718a


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