Cells often need to have polarity to function — cells lining the gut, for instance, secrete digestive enzymes only from their intestinal side. A protein called Bitesize is pivotal in determining which way is up.
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References
Pilot, F., Philippe, J.-M., Lemmers, C. & Lecuit, T. Nature 442, 580–584 (2006).
Tepass, U., Tanentzapf, G., Ward, R. & Fehon, R. Annu. Rev. Genet. 35, 747–784 (2001).
Bilder, D., Schober, M. & Perrimon, N. Nature Cell Biol. 5, 53–58 (2003).
Tanentzapf, G. & Tepass, U. Nature Cell Biol. 5, 46–52 (2003).
Harris, T. J. & Peifer, M. J. Cell Biol. 167, 135–147 (2004).
Harris, T. J. & Peifer, M. J. Cell Biol. 170, 813–823 (2005).
Serano, J. & Rubin, G. M. Proc. Natl Acad. Sci. USA 100, 13368–13373 (2003).
Fukuda, M. J. Biochem. (Tokyo) 137, 9–16 (2005).
von Stein, W., Ramrath, A., Grimm, A., Muller-Borg, M. & Wodarz, A. Development 132, 1675–1686 (2005).
Gates, J. & Peifer, M. Cell 123, 769–772 (2005).
Formstecher, E. et al. Genome Res. 15, 376–384 (2005).
Bretscher, A., Edwards, K. & Fehon, R. G. Nature Rev. Mol. Cell Biol. 3, 586–599 (2002).
Speck, O., Hughes, S. C., Noren, N. K., Kulikauskas, R. M. & Fehon, R. G. Nature 421, 83–87 (2003).
Hipfner, D. R., Keller, N. & Cohen, S. M. Genes Dev. 18, 2243–2248 (2004).
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Fehon, R. Polarity bites. Nature 442, 519–520 (2006). https://doi.org/10.1038/nature05036
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DOI: https://doi.org/10.1038/nature05036
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