Provider: Nature Publishing Group
Content: application/x-research-info-systems
TY  - JOUR
AU  - Kastan, M. B.
AU  - Lim, D. S.
TI  - The many substrates and functions of ATM
JA  - Nature Rev. Mol. Cell Biol.
PY  - 2000///
VL  - 1
SP  - 179
EP  - 186
M3  - 10.1038/35043058
N1  - 10.1038/35043058
UR  - http://dx.doi.org/10.1038/35043058
ER  -

TY  - JOUR
AU  - Pandita, T. K.
TI  - A multifaceted role for ATM in genome maintenance
JA  - Expert Rev. Mol. Med.
PY  - 2003///
VL  - 5
SP  - 1
EP  - 21
M3  - 10.1017/S1462399403006318
N1  - 10.1017/S1462399403006318
UR  - http://dx.doi.org/10.1017/S1462399403006318
ER  -

TY  - JOUR
AU  - Shiloh, Y.
TI  - ATM and related protein kinases: safeguarding genome integrity
JA  - Nature Rev. Cancer
PY  - 2003///
VL  - 3
SP  - 155
EP  - 168
M3  - 10.1038/nrc1011
N1  - 10.1038/nrc1011
UR  - http://dx.doi.org/10.1038/nrc1011
ER  -

TY  - JOUR
AU  - Durocher, D.
AU  - Jackson, S. P.
TI  - DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?
JA  - Curr. Opin. Cell Biol.
PY  - 2001///
VL  - 13
SP  - 225
EP  - 231
M3  - 10.1016/S0955-0674(00)00201-5
N1  - 10.1016/S0955-0674(00)00201-5
UR  - http://dx.doi.org/10.1016/S0955-0674(00)00201-5
ER  -

TY  - JOUR
AU  - Lavin, M. F.
AU  - Shiloh, Y.
TI  - The genetic defect in ataxia-telangiectasia
JA  - Annu. Rev. Immunol.
PY  - 1997///
VL  - 15
SP  - 177
EP  - 202
M3  - 10.1146/ANNUREV.IMMUNOL.15.1.177
N1  - 10.1146/ANNUREV.IMMUNOL.15.1.177
UR  - http://dx.doi.org/10.1146/ANNUREV.IMMUNOL.15.1.177
ER  -

TY  - JOUR
AU  - Taylor, A. M.
AU  - Metcalfe, J. A.
AU  - Thick, J.
AU  - Mak, Y. F.
TI  - Leukemia and lymphoma in ataxia telangiectasia
JA  - Blood
PY  - 1996///
VL  - 87
SP  - 423
EP  - 438
ER  -

TY  - JOUR
AU  - Tonegawa, S.
TI  - Somatic generation of antibody diversity
JA  - Nature
PY  - 1983///
VL  - 302
SP  - 575
EP  - 581
M3  - 10.1038/302575a0
N1  - 10.1038/302575a0
UR  - http://dx.doi.org/10.1038/302575a0
ER  -

TY  - JOUR
AU  - Fugmann, S. D.
AU  - Lee, A. I.
AU  - Shockett, P. E.
AU  - Villey, I. J.
AU  - Schatz, D. G.
TI  - The RAG proteins and V(D)J recombination: complexes, ends, and transposition
JA  - Annu. Rev. Immunol.
PY  - 2000///
VL  - 18
SP  - 495
EP  - 527
M3  - 10.1126/science.289.5476.77
N1  - 10.1126/science.289.5476.77
UR  - http://dx.doi.org/10.1126/science.289.5476.77
ER  -

TY  - JOUR
AU  - Oettinger, M. A.
TI  - V(D)J recombination: on the cutting edge
JA  - Curr. Opin. Cell Biol.
PY  - 1999///
VL  - 11
SP  - 325
EP  - 329
M3  - 10.1016/S0955-0674(99)80044-1
N1  - 10.1016/S0955-0674(99)80044-1
UR  - http://dx.doi.org/10.1016/S0955-0674(99)80044-1
ER  -

TY  - JOUR
AU  - Gellert, M.
TI  - V(D)J recombination: rag proteins, repair factors, and regulation
JA  - Annu. Rev. Biochem.
PY  - 2002///
VL  - 71
SP  - 101
EP  - 132
M3  - 10.1146/annurev.biochem.71.090501.150203
N1  - 10.1146/annurev.biochem.71.090501.150203
UR  - http://dx.doi.org/10.1146/annurev.biochem.71.090501.150203
ER  -

TY  - JOUR
AU  - Bassing, C. H.
AU  - Alt, F. W.
TI  - The cellular response to general and programmed DNA double strand breaks
JA  - DNA Repair (Amst.)
PY  - 2004///
VL  - 3
SP  - 781
EP  - 796
M3  - 10.1016/j.dnarep.2004.06.001
N1  - 10.1016/j.dnarep.2004.06.001
UR  - http://dx.doi.org/10.1016/j.dnarep.2004.06.001
ER  -

TY  - JOUR
AU  - Matei, I. R.
AU  - Guidos, C. J.
AU  - Danska, J. S.
TI  - ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection
JA  - Immunol. Rev.
PY  - 2006///
VL  - 209
SP  - 142
EP  - 158
M3  - 10.1111/j.0105-2896.2006.00361.x
N1  - 10.1111/j.0105-2896.2006.00361.x
UR  - http://dx.doi.org/10.1111/j.0105-2896.2006.00361.x
ER  -

TY  - JOUR
AU  - Perkins, E. J.
TI  - Sensing of intermediates in V(D)J recombination by ATM
JA  - Genes Dev.
PY  - 2002///
VL  - 16
SP  - 159
EP  - 164
M3  - 10.1101/gad.956902
N1  - 10.1101/gad.956902
UR  - http://dx.doi.org/10.1101/gad.956902
ER  -

TY  - JOUR
AU  - Liao, M. J.
AU  - Van Dyke, T.
TI  - Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma
JA  - Genes Dev.
PY  - 1999///
VL  - 13
SP  - 1246
EP  - 1250
ER  -

TY  - JOUR
AU  - Petiniot, L. K.
TI  - Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice
JA  - Proc. Natl Acad. Sci. USA
PY  - 2000///
VL  - 97
SP  - 6664
EP  - 6669
M3  - 10.1073/pnas.97.12.6664
N1  - 10.1073/pnas.97.12.6664
UR  - http://dx.doi.org/10.1073/pnas.97.12.6664
ER  -

TY  - JOUR
AU  - Donehower, L. A.
TI  - Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
JA  - Nature
PY  - 1992///
VL  - 356
SP  - 215
EP  - 221
M3  - 10.1038/356215a0
N1  - 10.1038/356215a0
UR  - http://dx.doi.org/10.1038/356215a0
ER  -

TY  - JOUR
AU  - Hirao, A.
TI  - Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
JA  - Mol. Cell. Biol.
PY  - 2002///
VL  - 22
SP  - 6521
EP  - 6532
M3  - 10.1128/MCB.22.18.6521-6532.2002
N1  - 10.1128/MCB.22.18.6521-6532.2002
UR  - http://dx.doi.org/10.1128/MCB.22.18.6521-6532.2002
ER  -

TY  - JOUR
AU  - Muljo, S. A.
AU  - Schlissel, M. S.
TI  - A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines
JA  - Nature Immunol.
PY  - 2003///
VL  - 4
SP  - 31
EP  - 37
M3  - 10.1038/ni870
N1  - 10.1038/ni870
UR  - http://dx.doi.org/10.1038/ni870
ER  -

TY  - JOUR
AU  - Liang, H. E.
TI  - The “dispensable” portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development
JA  - Immunity
PY  - 2002///
VL  - 17
SP  - 639
EP  - 651
M3  - 10.1016/S1074-7613(02)00448-X
N1  - 10.1016/S1074-7613(02)00448-X
UR  - http://dx.doi.org/10.1016/S1074-7613(02)00448-X
ER  -

TY  - JOUR
AU  - Lewis, S. M.
AU  - Hesse, J. E.
AU  - Mizuuchi, K.
AU  - Gellert, M.
TI  - Novel strand exchanges in V(D)J recombination
JA  - Cell
PY  - 1988///
VL  - 55
SP  - 1099
EP  - 1107
M3  - 10.1016/0092-8674(88)90254-1
N1  - 10.1016/0092-8674(88)90254-1
UR  - http://dx.doi.org/10.1016/0092-8674(88)90254-1
ER  -

TY  - JOUR
AU  - Morzycka-Wroblewska, E.
AU  - Lee, F. E.
AU  - Desiderio, S. V.
TI  - Unusual immunoglobulin gene rearrangement leads to replacement of recombinational signal sequences
JA  - Science
PY  - 1988///
VL  - 242
SP  - 261
EP  - 263
ER  -

TY  - JOUR
AU  - Hickson, I.
TI  - Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
JA  - Cancer Res.
PY  - 2004///
VL  - 64
SP  - 9152
EP  - 9159
M3  - 10.1158/0008-5472.CAN-04-2727
N1  - 10.1158/0008-5472.CAN-04-2727
UR  - http://dx.doi.org/10.1158/0008-5472.CAN-04-2727
ER  -

TY  - JOUR
AU  - Roth, D. B.
AU  - Menetski, J. P.
AU  - Nakajima, P. B.
AU  - Bosma, M. J.
AU  - Gellert, M.
TI  - V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
JA  - Cell
PY  - 1992///
VL  - 70
SP  - 983
EP  - 991
M3  - 10.1016/0092-8674(92)90248-B
N1  - 10.1016/0092-8674(92)90248-B
UR  - http://dx.doi.org/10.1016/0092-8674(92)90248-B
ER  -

TY  - JOUR
AU  - Franco, S.
TI  - H2AX prevents DNA breaks from progressing to chromosome breaks and translocations
JA  - Mol. Cell
PY  - 2006///
VL  - 21
SP  - 201
EP  - 214
M3  - 10.1016/j.molcel.2006.01.005
N1  - 10.1016/j.molcel.2006.01.005
UR  - http://dx.doi.org/10.1016/j.molcel.2006.01.005
ER  -

TY  - JOUR
AU  - Agrawal, A.
AU  - Schatz, D. G.
TI  - RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination
JA  - Cell
PY  - 1997///
VL  - 89
SP  - 43
EP  - 53
M3  - 10.1016/S0092-8674(00)80181-6
N1  - 10.1016/S0092-8674(00)80181-6
UR  - http://dx.doi.org/10.1016/S0092-8674(00)80181-6
ER  -

TY  - JOUR
AU  - Hiom, K.
AU  - Gellert, M.
TI  - Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination
JA  - Mol. Cell
PY  - 1998///
VL  - 1
SP  - 1011
EP  - 1019
M3  - 10.1016/S1097-2765(00)80101-X
N1  - 10.1016/S1097-2765(00)80101-X
UR  - http://dx.doi.org/10.1016/S1097-2765(00)80101-X
ER  -

TY  - JOUR
AU  - Riballo, E.
TI  - A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to [gamma]-H2AX foci
JA  - Mol. Cell
PY  - 2004///
VL  - 16
SP  - 715
EP  - 724
M3  - 10.1016/j.molcel.2004.10.029
N1  - 10.1016/j.molcel.2004.10.029
UR  - http://dx.doi.org/10.1016/j.molcel.2004.10.029
ER  -

TY  - JOUR
AU  - Sekiguchi, J. A.
AU  - Whitlow, S.
AU  - Alt, F. W.
TI  - Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs
JA  - Mol. Cell
PY  - 2001///
VL  - 8
SP  - 1383
EP  - 1390
M3  - 10.1016/S1097-2765(01)00423-3
N1  - 10.1016/S1097-2765(01)00423-3
UR  - http://dx.doi.org/10.1016/S1097-2765(01)00423-3
ER  -

TY  - JOUR
AU  - Mills, K. D.
AU  - Ferguson, D. O.
AU  - Alt, F. W.
TI  - The role of DNA breaks in genomic instability and tumorigenesis
JA  - Immunol. Rev.
PY  - 2003///
VL  - 194
SP  - 77
EP  - 95
M3  - 10.1034/j.1600-065X.2003.00060.x
N1  - 10.1034/j.1600-065X.2003.00060.x
UR  - http://dx.doi.org/10.1034/j.1600-065X.2003.00060.x
ER  -