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Nature 442, 365-366 (27 July 2006) | doi:10.1038/442365a; Published online 26 July 2006

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Developmental neurobiology: A destructive switch for neurons

Peter K. Jackson1

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In the developing nervous system, tremendous multiplication and diversification of cells elaborate the exquisite pattern of the brain. But how do cells shift from early proliferation to assume their mature states?

Control of cell division in the developing nervous system is a highly orchestrated process that sets up the patterns for the extended structure of the brain. In the embryonic brain, the division of neuroblasts — the precursors of neurons — occurs in specific proliferative zones.

  1. Peter K. Jackson is in the Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, and at Genentech Inc., 1 DNA Way, San Francisco, California 94080, USA.
    Email: pjackson@gene.com

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