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Nature 442, 381-386 (27 July 2006) | doi:10.1038/nature05060; Published online 26 July 2006

Developing optofluidic technology through the fusion of microfluidics and optics

Demetri Psaltis1, Stephen R. Quake2 and Changhuei Yang1

We describe devices in which optics and fluidics are used synergistically to synthesize novel functionalities. Fluidic replacement or modification leads to reconfigurable optical systems, whereas the implementation of optics through the microfluidic toolkit gives highly compact and integrated devices. We categorize optofluidics according to three broad categories of interactions: fluid–solid interfaces, purely fluidic interfaces and colloidal suspensions. We describe examples of optofluidic devices in each category.

  1. Department of Electrical Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  2. Department of Bioengineering, Stanford University and Howard Hughes Medical Institute, Stanford, California 94305, USA.

Correspondence to: Demetri Psaltis1 Email: psaltis@sunoptics.caltech.edu

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