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Nature 442, 114-115 (13 July 2006) | doi:10.1038/442114a; Published online 12 July 2006

Family tragedy spotlights flu mutations

Declan Butler

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Human-to-human transmission raises demand for DNA data.

A strain of avian flu that spread through a family in Indonesia, killing seven of the eight people infected, was accumulating mutations as it spread from person to person, according to confidential sequence data seen by Nature. The functional significance of the mutations isn't clear — most of them seem unimportant.

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