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Nature 442, 100-103 (21 May 2006) | doi:10.1038/nature04814;

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Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2

Covalent modifications of histone tails have a key role in regulating chromatin structure and controlling transcriptional activity. In eukaryotes, histone H3 trimethylated at lysine 4 (H3K4me3) is associated with active chromatin and gene expression.

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