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Editorials

Illuminating the black box p1

Note to biologists: submissions to Nature should contain complete descriptions of materials and reagents used.

doi:10.1038/442001a


Nuclear stalemates p2

The nuclear powers are maintaining their ageing stockpiles, without much thought or explanation.

doi:10.1038/442002a


Learning from Africa p2

Development projects need data as well as money.

doi:10.1038/442002b


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Research Highlights

Research highlights p4

doi:10.1038/442004a


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News

Planet-hunters seek cheap missions p6

Delayed NASA mission ushers in budget designs.

Geoff Brumfiel

doi:10.1038/442006a

See also: Editor's summary


Snapshot: Venus by day and night p7

European probe enters final orbit.

Jenny Hogan

doi:10.1038/442007a


Sociologist fools physics judges p8

But do social scientists understand science?

Jim Giles

doi:10.1038/442008a


Top five science blogs p9

Weblogs written by scientists are relatively rare, but some of them are proving popular. Out of 46.7 million blogs indexed by the Technorati blog search engine, five scientists' sites make it into the top 3,500. Declan Butler asks the winners about the reasons for their success.

doi:10.1038/442009a


Simple recipe gives adult cells embryonic powers p11

Just four factors are enough to reprogramme mouse cells.

Erika Check

doi:10.1038/442011a


Sidelines p11

doi:10.1038/442011b


Doing conservation by numbers p12

Biologists try business-like approach to saving tigers.

Rex Dalton

doi:10.1038/442012a


Should conservation biologists push policies? p13

To advocate or not advocate?

Emma Marris

doi:10.1038/442013a


News in brief p15

doi:10.1038/442015a


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Business

Big Blue in deep p17

India is traditionally suspicious of multinationals. So IBM's huge investment plan has provoked a mixed response, reports K. S. Jayaraman.

doi:10.1038/442017a


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News Features

Nuclear weapons: The next nuke p18

US nuclear weapons scientists are designing a warhead that is meant to be 'reliable' without ever having been tested. Geoff Brumfiel asks whether it could renew the United States' ageing stockpile.

doi:10.1038/442018a

See also: Editor's summary


Development: Harvest of hope p22

An economist believes that a five-year aid effort in a dozen villages across Africa can teach the world how to defeat poverty. Sarah Tomlin reports on the project's progress in Rwanda.

doi:10.1038/442022a

See also: Editor's summary


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Correspondence

Reviewers' reports should in turn be peer reviewed p26

Alexandra List

doi:10.1038/442026a


Judge a paper on its own merits, not its journal's p26

Shu-Dong Zhang

doi:10.1038/442026b


Unpredictable Sun leaves researchers in the dark p26

Steven Tobias, David Hughes & Nigel Weiss

doi:10.1038/442026c


Second thoughts on who goes where in author lists p26

William F. Laurance

doi:10.1038/442026d


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Books and Arts

Changing our minds p27

Our environment can affect the way our minds develop, but the relationship is complex.

Paul Bloom reviews Brain and Culture: Neurobiology, Ideology, and Social Change by Bruce E. Wexler

doi:10.1038/442027a


A turbulent history p28

Roddam Narasimha reviews Worlds of Flow: A History of Hydrodynamics from the Bernoullis to Prandtl by Olivier Darrigol

doi:10.1038/442028a


Science in Culture p28

A sculptural approach to the heart.

Philip J. Kilner

doi:10.1038/442029a


Floral attraction p30

Sebsebe Demissew reviews An Enthusiasm for Orchids: Sex and Deception in Plant Evolution by John Alcock

doi:10.1038/442030a


The maths mentor p30

Rhian Parker reviews Letters to a Young Mathematician by Ian Stewart

doi:10.1038/442030b

See also: Editor's summary


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News and Views

Gene regulation: A finger on the mark p31

Chromatin, the protein wrapping of the genome, harbours information about how the genes it contains are to be regulated. Are we any closer to deciphering these encoded instructions?

Peter B. Becker

doi:10.1038/442031a

See also: Editor's summary


Condensed-matter physics: Superfluidity in the picture p32

Strongly interacting atomic Fermi gases — useful models for many other exotic forms of matter — enter a superfluid state at low temperatures. The first direct observation of that transition has been made.

J. E. Thomas

doi:10.1038/442032a


Virology: Micro mystery solution p33

A particular talent of herpes simplex virus-1 is that it can lurk unseen in the cells of an infected person for long periods. It turns out that the virus achieves this feat through the agency of a microRNA.

Bill Sugden

doi:10.1038/442033a

See also: Editor's summary


50 & 100 years ago p34

doi:10.1038/442034a


Microscopy: X-ray nanovision p35

Startling three-dimensional images of nanoparticles have been obtained with an X-ray microscope, showing crystal deformation in unprecedented detail. The trick is not to focus the X-rays, but to diffract them.

Eric D. Isaacs

doi:10.1038/442035a

See also: Editor's summary


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Brief Communications

Avian Flu: Multiple introductions of H5N1 in Nigeria p37

Phylogenetic analysis reveals that this deadly virus first arrived in Africa from different sources.

M. F. Ducatez, C. M. Olinger, A. A. Owoade, S. De Landtsheer, W. Ammerlaan, H. G. M. Niesters, A. D. M. E. Osterhaus, R. A. M. Fouchier & C. P. Muller

doi:10.1038/442037a

See also: Editor's summary


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Brief Communications Arising

Intelligence: Is there a sex difference in IQ scores? pE1

Paul Irwing & Richard Lynn

doi:10.1038/nature04966


Intelligence: Is there a sex difference in IQ scores? (Reply) pE1

Steve Blinkhorn

doi:10.1038/nature04967


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Review

Intracellular pattern recognition receptors in the host response p39

Etienne Meylan, Jürg Tschopp & Michael Karin

doi:10.1038/nature04946

See also: Editor's summary


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Article

Selective elimination of messenger RNA prevents an incidence of untimely meiosis p45

Yuriko Harigaya, Hirotsugu Tanaka, Soichiro Yamanaka, Kayoko Tanaka, Yoshinori Watanabe, Chihiro Tsutsumi, Yuji Chikashige, Yasushi Hiraoka, Akira Yamashita & Masayuki Yamamoto

doi:10.1038/nature04881

See also: Editor's summary


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Letters

Detection of Earth-like planets around nearby stars using a petal-shaped occulter p51

Webster Cash

doi:10.1038/nature04930

See also: Editor's summary


Direct observation of the superfluid phase transition in ultracold Fermi gases p54

Martin W. Zwierlein, Christian H. Schunck, André Schirotzek & Wolfgang Ketterle

doi:10.1038/nature04936

See also: News and Views by Thomas


Resonance in the electron-doped high-transition-temperature superconductor Pr0.88LaCe0.12CuO4-delta p59

Stephen D. Wilson, Pengcheng Dai, Shiliang Li, Songxue Chi, H. J. Kang & J. W. Lynn

doi:10.1038/nature04857


Three-dimensional mapping of a deformation field inside a nanocrystal p63

Mark A. Pfeifer, Garth J. Williams, Ivan A. Vartanyants, Ross Harder & Ian K. Robinson

doi:10.1038/nature04867

See also: Editor's summary


The effect of energy feedbacks on continental strength p67

Klaus Regenauer-Lieb, Roberto F. Weinberg & Gideon Rosenbaum

doi:10.1038/nature04868

See also: Editor's summary


Earthquakes triggered by silent slip events on Kbold imacrlauea volcano, Hawaii p71

Paul Segall, Emily K. Desmarais, David Shelly, Asta Miklius & Peter Cervelli

doi:10.1038/nature04938

See also: Editor's summary


Local migration promotes competitive restraint in a host–pathogen 'tragedy of the commons' p75

Benjamin Kerr, Claudia Neuhauser, Brendan J. M. Bohannan & Antony M. Dean

doi:10.1038/nature04864

See also: Editor's summary


Retroviral invasion of the koala genome p79

Rachael E. Tarlinton, Joanne Meers & Paul R. Young

doi:10.1038/nature04841

See also: Editor's summary


Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript p82

A. Gupta, J. J. Gartner, P. Sethupathy, A. G. Hatzigeorgiou & N. W. Fraser

doi:10.1038/nature04836

See also: Editor's summary | News and Views by Sugden


A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling p86

Joanna Wysocka, Tomek Swigut, Hua Xiao, Thomas A. Milne, So Yeon Kwon, Joe Landry, Monika Kauer, Alan J. Tackett, Brian T. Chait, Paul Badenhorst, Carl Wu & C. David Allis

doi:10.1038/nature04815

See also: Editor's summary


Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF p91

Haitao Li, Serge Ilin, Wooikoon Wang, Elizabeth M. Duncan, Joanna Wysocka, C. David Allis & Dinshaw J. Patel

doi:10.1038/nature04802

See also: Editor's summary


ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression p96

Xiaobing Shi, Tao Hong, Kay L. Walter, Mark Ewalt, Eriko Michishita, Tiffany Hung, Dylan Carney, Pedro Peña, Fei Lan, Mohan R. Kaadige, Nicolas Lacoste, Christelle Cayrou, Foteini Davrazou, Anjanabha Saha, Bradley R. Cairns, Donald E. Ayer, Tatiana G. Kutateladze, Yang Shi, Jacques Côté, Katrin F. Chua & Or Gozani

doi:10.1038/nature04835

See also: Editor's summary


Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2 p100

Pedro V. Peña, Foteini Davrazou, Xiaobing Shi, Kay L. Walter, Vladislav V. Verkhusha, Or Gozani, Rui Zhao & Tatiana G. Kutateladze

doi:10.1038/nature04814

See also: Editor's summary


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Naturejobs

Prospect

Prospect p105

International panel seeks more representation of women in science.

Paul Smaglik

doi:10.1038/nj7098-105a


Career Views

Ed Holmes, executive deputy chairman, Biomedical Research Council, Singapore; and Judith Swain, executive director, Singapore Institute for Clinical Sciences. p106

Holmes and Swain head to Singapore's Biopolis.

Janet Wright

doi:10.1038/nj7098-106a


The right advice p106

Mentoring award recipient reaches out to geosciences students.

Tanya Furman

doi:10.1038/nj7098-106b


Stumbling at the finish line p106

Distractions multiply as thesis work intensifies.

Andreas Andersson

doi:10.1038/nj7098-106c


Highlights

Highlight: The National Institutes of Health

doi:10.1038/nj0121


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Futures

Semi-autonomous p108

Ask not for whom the warranty tolls.

Jim Kling

doi:10.1038/442108a


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