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Nature 442, 33-34 (6 July 2006) | doi:10.1038/442033a; Published online 5 July 2006
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Virology: Micro mystery solution
Bill Sugden1
Abstract
A particular talent of herpes simplex virus-1 is that it can lurk unseen in the cells of an infected person for long periods. It turns out that the virus achieves this feat through the agency of a microRNA.
Herpes simplex virus-1 (HSV-1) infects most of us but then stays hidden for most of our lives. When it does re-emerge, the virus usually causes cold sores; its close cousin, HSV-2, can likewise hide, then re-emerge to cause distressing and painful genital sores.
- Bill Sugden is in the McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin 53706, USA.
Email: sugden@oncology.wisc.edu
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