Table of contents
Volume 441 Number 7097 pp1027-1194
Editorials
Science in the Arab world p1027
The immense challenges facing those who attempt to support research in developing countries are compounded by political turmoil in the Middle East.
doi:10.1038/4411027a
See also: Editor's summary
A tale of one world p1028
Celebrating science on the solstice.
doi:10.1038/4411028a
Action stations p1028
The time for sitting on flu data is over.
doi:10.1038/4411028b
News
Academy affirms hockey-stick graph p1032
But it criticizes the way the controversial climate result was used.
Geoff Brumfiel
doi:10.1038/4411032a
Experts comb tropics for clues to vCJD p1033
Fate of ex-cannibals suggests prion diseases can incubate for half a century.
Helen Pearson
doi:10.1038/4411033a
Sidelines p1034
doi:10.1038/4411034a
Hungary's science academy slammed as 'obsolete' p1034
Government and researchers complain of old-fashioned and discriminatory policies.
Quirin Schiermeier
doi:10.1038/4411034b
Hunt for AIDS vaccine tackles genomes p1034
Systematic search for HIV immunity proposed.
Erika Check
doi:10.1038/4411034c
Scientists become targets in Iraq p1036
Violence is common currency in Iraq, but one group is increasingly and persistently singled out — academics. Declan Butler reports on the risks run by researchers as they struggle to pursue their studies.
doi:10.1038/4411036a
Human eggs supply 'ethical' stem cells p1038
Use of parthenogenetic lines could side step moral issues.
Jo Marchant
doi:10.1038/4411038a
News in brief p1039
doi:10.1038/4411039a
Correction p1039
doi:10.1038/4411039a
News Feature
Science on the solstice p1040
Every day, all over the planet and beyond it, scientists try to make sense of the world in which they live. Here we present a composite picture of just one day — 21 June 2006, the Northern summer solstice.
doi:10.1038/4411040a
See also: Editor's summary
Business
Assault on batteries p1046
Miniature fuel cells are being developed as an alternative way to power portable devices. But they're not ready yet, as Kurt Kleiner reports.
doi:10.1038/4411046a
See also: Editor's summary
In brief p1047
doi:10.1038/4411047a
Market watch p1047
Colin Macilwain
doi:10.1038/4411047b
Correspondence
Seeing is believing as brain reveals its adaptability p1048
Oliver Sacks and Ralph M. Siegel
doi:10.1038/4411048a
Discrete reminder about Weismann's discovery p1048
William L. Abler
doi:10.1038/4411048b
Researchers frustrated by lack of input to NIH policy p1048
Don C. Rockey
doi:10.1038/4411048c
Public will fear biological accidents, not just attacks p1048
Markus Schmidt
doi:10.1038/4411048d
Correction p1048
doi:10.1038/4411048e
Books and Arts
Faster, better, healthier p1049
An exploration of how genetics has influenced many aspects of life.
Michael A. Goldman reviews The Strongest Boy In The World: How Genetic Information Is Reshaping Our Lives by Philip R. Reilly
doi:10.1038/4411049a
A glimpse of the early Universe p1050
Patrick Petitjean reviews Chasing Hubble's Shadows: The Search for Galaxies at the Edge of Time by Jeff Kanipe
doi:10.1038/4411050a
A question of taste p1051
John Piggott reviews Molecular Gastronomy: Exploring the Science of Flavor by Hervé This
doi:10.1038/4411051a
Correction p1051
doi:10.1038/4411051b
News and Views
Quantum physics: Atomic gas in flatland p1053
The observation of Bose–Einstein condensation in an atomic gas was a seminal result. Two-dimensional gases are more complex, and an intriguing interference experiment has exposed a different superfluid transition.
Tilman Esslinger and Gianni Blatter
doi:10.1038/4411053a
See also: Editor's summary
Structural biology: RNA switches function p1054
Proteins are not the only regulators of metabolite synthesis — some RNA molecules do it too. These RNAs lack chemical diversity, so how do we explain the variety of their respective substrates?
Steve Reichow and Gabriele Varani
doi:10.1038/4411054a
See also: Editor's summary
Materials science: Germanium takes holey orders p1055
Soap-like molecules serve as a scaffold for remarkably well-ordered, porous germanium skeletons. The nanometre-sized features of these semiconductor frameworks confer unique optical and electronic properties.
Andreas Stein
doi:10.1038/4411055a
See also: Editor's summary
Astronomy: Supernovae brought to light p1056
The existing catalogue of Galactic supernova remnants contains only a small fraction of the true number of these stellar explosions. A different observational technique is being employed to find the missing ones.
Carl Heiles
doi:10.1038/4411056a
Neurodegenerative disease: Pink, parkin and the brain p1058
Dysfunctions in a number of cellular pathways can cause Parkinson's disease. Fruitflies with mutations in a protein called PINK1 show that there might be some unsuspected interplay between two such pathways.
Leo Pallanck and J. Timothy Greenamyre
doi:10.1038/4411058a
See also: Editor's summary
Insight: Stem-cell Biology -
Produced with support from:
Insight: Stem-cell Biology
Stem-cell Biology p1059
Natalie DeWitt
doi:10.1038/4411059a
A glossary for stem-cell biology p1060
Austin Smith
doi:10.1038/nature04954
Abstract | Full Text | PDF (68K)
Nuclear reprogramming and pluripotency p1061
Konrad Hochedlinger and Rudolf Jaenisch
doi:10.1038/nature04955
Abstract | Full Text | PDF (644K)
Asymmetric and symmetric stem-cell divisions in development and cancer p1068
Sean J. Morrison and Judith Kimble
doi:10.1038/nature04956
Abstract | Full Text | PDF (473K)
The stem-cell niche as an entity of action p1075
David T. Scadden
doi:10.1038/nature04957
Abstract | Full Text | PDF (323K)
Stem cells, ageing and the quest for immortality p1080
Thomas A. Rando
doi:10.1038/nature04958
Abstract | Full Text | PDF (641K)
Generation of neuronal variability and complexity p1087
Alysson R. Muotri and Fred H. Gage
doi:10.1038/nature04959
Abstract | Full Text | PDF (756K)
Stem cells for the treatment of neurological disorders p1094
Olle Lindvall and Zaal Kokaia
doi:10.1038/nature04960
Abstract | Full Text | PDF (402K)
Potential of stem-cell-based therapies for heart disease p1097
Deepak Srivastava and Kathryn N. Ivey
doi:10.1038/nature04961
Abstract | Full Text | PDF (345K)
Stem-cell therapies for blood diseases p1100
Claudio Bordignon
doi:10.1038/nature04962
Abstract | Full Text | PDF (323K)
Articles
Genetic evidence for complex speciation of humans and chimpanzees p1103
Nick Patterson, Daniel J. Richter, Sante Gnerre, Eric S. Lander and David Reich
doi:10.1038/nature04789
Abstract | Full Text | PDF (327K) | Supplementary information
See also: Editor's summary
Ovulated oocytes in adult mice derive from non-circulating germ cells p1109
Kevin Eggan, Sara Jurga, Roger Gosden, Irene M. Min and Amy J. Wagers
doi:10.1038/nature04929
Abstract | Full Text | PDF (581K) | Supplementary information
See also: Editor's summary
Letters
Soft equations of state for neutron-star matter ruled out by EXO 0748 - 676 p1115
F. Özel
doi:10.1038/nature04858
First paragraph | Full Text | PDF (202K)
See also: Editor's summary
Berezinskii–Kosterlitz–Thouless crossover in a trapped atomic gas p1118
Zoran Hadzibabic, Peter Krüger, Marc Cheneau, Baptiste Battelier and Jean Dalibard
doi:10.1038/nature04851
First paragraph | Full Text | PDF (280K)
See also: Editor's summary
Mesostructured germanium with cubic pore symmetry p1122
Gerasimos S. Armatas and Mercouri G. Kanatzidis
doi:10.1038/nature04833
First paragraph | Full Text | PDF (654K) | Supplementary information
See also: Editor's summary
Hexagonal nanoporous germanium through surfactant-driven self-assembly of Zintl clusters p1126
Dong Sun, Andrew E. Riley, Ashley J. Cadby, Erik K. Richman, Scott D. Korlann and Sarah H. Tolbert
doi:10.1038/nature04891
First paragraph | Full Text | PDF (442K) | Supplementary information
See also: Editor's summary
Subcontinental-scale crustal velocity changes along the Pacific–North America plate boundary p1131
J. L. Davis, B. P. Wernicke, S. Bisnath, N. A. Niemi and P. Elósegui
doi:10.1038/nature04781
First paragraph | Full Text | PDF (2,092K)
See also: Editor's summary
Seismic waves increase permeability p1135
Jean E. Elkhoury, Emily E. Brodsky and Duncan C. Agnew
doi:10.1038/nature04798
First paragraph | Full Text | PDF (1,377K) | Supplementary information
See also: Editor's summary
Diversity and dispersal interactively affect predictability of ecosystem function p1139
Kristin E. France and J. Emmett Duffy
doi:10.1038/nature04729
First paragraph | Full Text | PDF (298K) | Supplementary information
See also: Editor's summary
Activity-dependent dynamics and sequestration of proteasomes in dendritic spines p1144
Baris Bingol and Erin M. Schuman
doi:10.1038/nature04769
First paragraph | Full Text | PDF (669K) | Supplementary information
See also: Editor's summary
Nodulation independent of rhizobia induced by a calcium-activated kinase lacking autoinhibition p1149
Cynthia Gleason, Shubho Chaudhuri, Tianbao Yang, Alfonso Muñoz, B. W. Poovaiah and Giles E. D. Oldroyd
doi:10.1038/nature04812
First paragraph | Full Text | PDF (301K) | Supplementary information
See also: Editor's summary
Deregulation of a Ca2+/calmodulin-dependent kinase leads to spontaneous nodule development p1153
Leïla Tirichine, Haruko Imaizumi-Anraku, Satoko Yoshida, Yasuhiro Murakami, Lene H. Madsen, Hiroki Miwa, Tomomi Nakagawa, Niels Sandal, Anita S. Albrektsen, Masayoshi Kawaguchi, Allan Downie, Shusei Sato, Satoshi Tabata, Hiroshi Kouchi, Martin Parniske, Shinji Kawasaki and Jens Stougaard
doi:10.1038/nature04862
First paragraph | Full Text | PDF (400K) | Supplementary information
See also: Editor's summary
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin p1157
Jeehye Park, Sung Bae Lee, Sungkyu Lee, Yongsung Kim, Saera Song, Sunhong Kim, Eunkyung Bae, Jaeseob Kim, Minho Shong, Jin-Man Kim and Jongkyeong Chung
doi:10.1038/nature04788
First paragraph | Full Text | PDF (627K) | Supplementary information
See also: Editor's summary
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin p1162
Ira E. Clark, Mark W. Dodson, Changan Jiang, Joseph H. Cao, Jun R. Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A. Hay and Ming Guo
doi:10.1038/nature04779
First paragraph | Full Text | PDF (545K) | Supplementary information
See also: Editor's summary
Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch p1167
Alexander Serganov, Anna Polonskaia, Anh Tuân Phan, Ronald R. Breaker and Dinshaw J. Patel
doi:10.1038/nature04740
First paragraph | Full Text | PDF (1,000K) | Supplementary information
See also: Editor's summary
Structure of the S-adenosylmethionine riboswitch regulatory mRNA element p1172
Rebecca K. Montange and Robert T. Batey
doi:10.1038/nature04819
First paragraph | Full Text | PDF (430K) | Supplementary information
See also: Editor's summary
Retraction: Induction of DNA methylation and gene silencing by short interfering RNAs in human cells p1176
Hiroaki Kawasaki and Kazunari Taira
doi:10.1038/nature04952
Technology Features
Cell sorting: Divide and conquer p1179
A key element of performing good cell-biology experiments is starting with exactly the right cells. Michael Eisenstein takes a look at the technologies that can make this possible.
Michael Eisenstein
doi:10.1038/4411179a
See also: Editor's summary
Cell sorting: The gentle touch p1179
doi:10.1038/4411179b
Cell sorting: Playing the field p1181
doi:10.1038/4411181a
Cell sorting: The guiding light p1183
doi:10.1038/4411183a
Naturejobs
ProspectProspect p1191
Research assessment threatens to reshuffle UK funding.
Paul Smaglik
doi:10.1038/nj7097-1191a
Career Views
Gary Borisy, director and chief executive, Marine Biological Laboratory, Woods Hole, Massachusetts p1192
Gary Borisy takes the helm at the Marine Biological Laboratory.
Virginia Gewin
doi:10.1038/nj7097-1192a
Networks work p1192
Networking can pay off for PhD students.
Denis Bilotta
doi:10.1038/nj7097-1192b
Goooaaalll! A PhD! p1192
Thesis excitement rivals the World Cup.
Milan de Vries
doi:10.1038/nj7097-1192c
Futures
Finding a happy medium p1194
Be careful what you think out loud...
John Gilbey
doi:10.1038/4411194a
