Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 441, 1097-1099 (29 June 2006) | doi:10.1038/nature04961; Published online 28 June 2006
There is a Corrigendum (23 November 2006) associated with this document.
Progress Potential of stem-cell-based therapies for heart disease
Deepak Srivastava1 & Kathryn N. Ivey1
Abstract
The use of stem cells to generate replacement cells for damaged heart muscle, valves, vessels and conduction cells holds great potential. Recent identification of multipotent progenitor cells in the heart and improved understanding of developmental processes relevant to pluripotent embryonic stem cells may facilitate the generation of specific types of cell that can be used to treat human heart disease. Secreted factors from circulating progenitor cells that localize to sites of damage may also be useful for tissue protection or neovascularization. The exciting discoveries in basic science will require rigorous testing in animal models to determine those most worthy of future clinical trials.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Akt helps stem cells heal the heartNature Medicine News and Views (01 Sep 2003)
5b+D6Z+z44KS5Yi744KA6IOa5oCn5bm557Sw6IOeNature Biotechnology News and Views (01 Oct 2004)