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Nature 441, 1033 (29 June 2006) | doi:10.1038/4411033a; Published online 28 June 2006

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Experts comb tropics for clues to vCJD

Helen Pearson

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Fate of ex-cannibals suggests prion diseases can incubate for half a century.

Some people in Papua New Guinea who once feasted on their own relatives did not succumb to the prion disease kuru until 50 years later, say researchers who have laboriously tracked down the last sufferers in remote villages. The discovery renews concern that another human prion disease, variant Creutzfeldt–Jakob disease (vCJD), might be incubating silently in some populations and could rear its head decades from now.