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Review
Nature 441, 947-952 (22 June 2006) | doi:10.1038/nature04878
nature jobs
Research Psychiatrist
- Scripps Research Institute
- La Jolla, CA
Laboratory Manager / Principal Research Assistant
- Wellcome Trust Sanger Institute
- Hinxton, Cambridge, CB10 1SA, UK
Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis
Thomas Mitchell-Olds1 & Johanna Schmitt2
Abstract
Genomic studies of natural variation in model organisms provide a bridge between molecular analyses of gene function and evolutionary investigations of adaptation and natural selection. In the model plant species Arabidopsis thaliana, recent studies of natural variation have led to the identification of genes underlying ecologically important complex traits, and provided new insights about the processes of genome evolution, geographic population structure, and the selective mechanisms shaping complex trait variation in natural populations. These advances illustrate the potential for a new synthesis to elucidate mechanisms for the adaptive evolution of complex traits from nucleotide sequences to real-world environments.
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