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Authors

Making the paper: Irina Marinov pxi

An in-depth look at how the oceans take up carbon dioxide.

doi:10.1038/7096xia


Abstractions pxi

doi:10.1038/7096xib


On the web: Open peer-review debate pxi

doi:10.1038/7096xic


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Editorials

Neuroethics needed p907

Researchers should speak out on claims made on behalf of their science.

doi:10.1038/441907a


Urgent but balanced p907

Energy problems demand a coherent solution, not a quick fix.

doi:10.1038/441907b


The mad technologist p908

Hollywood warms to science, but fears technology.

doi:10.1038/441908a


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Research Highlights

Research highlights p910

doi:10.1038/441910a


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News

Tissue-sample payments anger lawmakers p912

Drug company link could hit biobank plans.

Erika Check

doi:10.1038/441912a


Doomsday food store takes pole position p912

Remote island hosts global seed bank.

Jacqueline Ruttimann

doi:10.1038/441912b


Sidelines p913

doi:10.1038/441913a


Open-access journal hits rocky times p914

Financial analysis reveals reliance on philanthropy.

Declan Butler

doi:10.1038/441914a


Congress pushes plan to make papers free p915

NIH may have to insist on submission to online archive.

Gene Russo

doi:10.1038/441915a


Plan to rank universities fails to impress p917

Government risks undermining basic research, say critics.

Jim Giles

doi:10.1038/441917a


Lure of lie detectors spooks ethicists p918

US companies are planning to profit from lie-detection technology that uses brain scans, but the move to commercialize a little-tested method is ringing ethical and scientific alarm bells. Helen Pearson reports.

doi:10.1038/441918a


News in brief p920

doi:10.1038/441920a


Correction p921

doi:10.1038/441921a


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News Features

Science in the movies: From microscope to multiplex - An MRI scanner darkly p922

There's more to science at the movies than Lex Luthor's attempts to synthesize kryptonite. In the first of two features on film, John Whitfield looks at how a cinematographic technique can provide insights into the perception of reality. In the second, Alison Abbott meets Ben Heisenberg, a director whose first film is a taut moral fable of laboratory life.

doi:10.1038/441922a


Science in the movies: From microscope to multiplex - Betrayal at the bench p924

There's more to science at the movies than Lex Luthor's attempts to synthesize kryptonite. In the first of two features on film, John Whitfield looks at how a cinematographic technique can provide insights into the perception of reality. In the second, Alison Abbott meets Ben Heisenberg, a director whose first film is a taut moral fable of laboratory life.

doi:10.1038/441924a


Conservation biology: The tiger's retreat p927

Tigers are teetering on the verge of extinction and human contact in their habitat could be their greatest threat. Erika Check investigates whether local people can live alongside India's big cats.

doi:10.1038/441927a

See also: Editor's summary


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Business

Angling Saxons p931

Eastern Germany is landing major electronics industry investments — but needs to build up its own innovative capacity, reports Ned Stafford.

doi:10.1038/441931a


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Correspondence

Misconduct: lack of action provokes web accusations p932

Shi-min Fang

doi:10.1038/441932a


Misconduct: exposure is not like Cultural Revolution p932

Zheng Huang

doi:10.1038/441932b


Misconduct: Chinese funding body unmoved p932

Ushma Savla Neill

doi:10.1038/441932c


Education and training put Iran ahead of richer states p932

Mohammad Reza Mohebbi and Mehri Mohebbi

doi:10.1038/441932d


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Books and Arts

Lessons from Italy p933

How malaria affected, and was controlled in, Italy in the past century has important messages for today.

Brian Greenwood reviews The Conquest of Malaria: Italy, 1900–1962 by Frank M. Snowden

doi:10.1038/441933a


Life under the microscope p934

Jane Maienschein reviews The Egg and Sperm Race: The Seventeenth-Century Scientists Who Unravelled the Secrets of Sex, Life and Growth by Matthew Cobb

doi:10.1038/441934a


Virtually wild p935

doi:10.1038/441935a


A weird, wired world p935

Vlatko Vedral reviews Entangled World: The Fascination of Quantum Information and Computation edited by Jürgen Audretsch

doi:10.1038/441935b


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News and Views

Animal behaviour: Trust in fish p937

A mutually beneficial interaction between two species of fish turns out to involve the careful appraisal of one by the other — and the appropriately virtuous behaviour by the former while being watched.

Lee Alan Dugatkin

doi:10.1038/441937a

See also: Editor's summary


Astrophysics: Magnetic accretion p938

Disks of hot gas drawn onto a central star or black hole are the best energy-producing machines in the Universe. So how do these accretion disks work? The answer, it seems, is blowing in their winds.

Daniel Proga

doi:10.1038/441938a

See also: Editor's summary


Cell biology: The Golgi grows up p939

The Golgi apparatus of the cell has long baffled biologists, mainly because it is unclear how proteins are conveyed through it on their way to the cell surface. Some innovative microscopy may resolve the issue.

Vivek Malhotra and Satyajit Mayor

doi:10.1038/441939a

See also: Editor's summary


Plant biology: Designs on Rubisco p940

Rubisco is said to be both the most important enzyme on Earth and surprisingly inefficient. Yet an understanding of the reaction by which it fixes CO2 suggests that evolution has made the best of a bad job.

Howard Griffiths

doi:10.1038/441940a


Materials science: Relaxors go critical p941

Relaxor ferroelectrics are fascinating and useful materials, but they seem to be heterogeneous, hopeless messes. Observing what they do under electric fields reveals critical behaviour that helps to make sense of them.

R. E. Cohen

doi:10.1038/441941a

See also: Editor's summary


Immunology: A second chance for the thymus p942

Each organ develops at its own time — usually in the embryo. The discovery of progenitor cells that give rise to two structures in the thymus hints that this immune organ can continue to develop after birth.

Hans-Reimer Rodewald

doi:10.1038/441942a

See also: Editor's summary


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Brief Communications

Pollination: Self-fertilization strategy in an orchid p945

An orchid that flowers in harsh conditions pollinates itself unassisted by any of the usual agents.

Ke-Wei Liu, Zhong-Jian Liu, LaiQiang Huang, Li-Qiang Li, Li-Jun Chen and Guang-Da Tang

doi:10.1038/441945a

See also: Editor's summary


Photonics: Lasers producing tailored beams p946

Eiji Miyai, Kyosuke Sakai, Takayuki Okano, Wataru Kunishi, Dai Ohnishi and Susumu Noda

doi:10.1038/441946a


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Brief Communications Arising

Sleep behaviour: Sleep in continuously active dolphins pE9

Yuske Sekiguchi, Kazutoshi Arai and Shiro Kohshima

doi:10.1038/nature04898

See also: Editor's summary


Sleep behaviour: Activity and sleep in dolphins pE10

Guido Gnone, Tiziana Moriconi and Giorgia Gambini

doi:10.1038/nature04899


Sleep behaviour: Sleep in continuously active dolphins; Activity and sleep in dolphins (Reply) pE11

O. I. Lyamin, J. Pryaslova, V. Lance and J. M. Siegel

doi:10.1038/nature04900


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Review

Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis p947

Thomas Mitchell-Olds and Johanna Schmitt

doi:10.1038/nature04878

See also: Editor's summary


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Letters

The magnetic nature of disk accretion onto black holes p953

Jon M. Miller, John Raymond, Andy Fabian, Danny Steeghs, Jeroen Homan, Chris Reynolds, Michiel van der Klis and Rudy Wijnands

doi:10.1038/nature04912

See also: Editor's summary | News and Views by Proga


The giant electromechanical response in ferroelectric relaxors as a critical phenomenon p956

Z. Kutnjak, J. Petzelt and R. Blinc

doi:10.1038/nature04854

See also: Editor's summary | News and Views by Cohen


Broad-band optical parametric gain on a silicon photonic chip p960

Mark A. Foster, Amy C. Turner, Jay E. Sharping, Bradley S. Schmidt, Michal Lipson and Alexander L. Gaeta

doi:10.1038/nature04932

See also: Editor's summary


The Southern Ocean biogeochemical divide p964

I. Marinov, A. Gnanadesikan, J. R. Toggweiler and J. L. Sarmiento

doi:10.1038/nature04883


Interseismic strain accumulation and the earthquake potential on the southern San Andreas fault system p968

Yuri Fialko

doi:10.1038/nature04797

See also: Editor's summary


A lamprey from the Cretaceous Jehol biota of China p972

Mee-mann Chang, Jiangyong Zhang and Desui Miao

doi:10.1038/nature04730

See also: Editor's summary


Image scoring and cooperation in a cleaner fish mutualism p975

Redouan Bshary and Alexandra S. Grutter

doi:10.1038/nature04755

See also: Editor's summary | News and Views by Dugatkin


Experience-dependent and cell-type-specific spine growth in the neocortex p979

Anthony Holtmaat, Linda Wilbrecht, Graham W. Knott, Egbert Welker and Karel Svoboda

doi:10.1038/nature04783


Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells p984

Patricia M. White, Angelika Doetzlhofer, Yun Shain Lee, Andrew K. Groves and Neil Segil

doi:10.1038/nature04849

See also: Editor's summary


Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium p988

Simona W. Rossi, William E. Jenkinson, Graham Anderson and Eric J. Jenkinson

doi:10.1038/nature04813

See also: Editor's summary | News and Views by Rodewald


Formation of a functional thymus initiated by a postnatal epithelial progenitor cell p992

Conrad C. Bleul, Tatiana Corbeaux, Alexander Reuter, Paul Fisch, Jürgen Schulte Mönting and Thomas Boehm

doi:10.1038/nature04850

See also: Editor's summary | News and Views by Rodewald


Nanog promotes transfer of pluripotency after cell fusion p997

José Silva, Ian Chambers, Steven Pollard and Austin Smith

doi:10.1038/nature04914


Golgi maturation visualized in living yeast p1002

Eugene Losev, Catherine A. Reinke, Jennifer Jellen, Daniel E. Strongin, Brooke J. Bevis and Benjamin S. Glick

doi:10.1038/nature04717

See also: Editor's summary


Live imaging of yeast Golgi cisternal maturation p1007

Kumi Matsuura-Tokita, Masaki Takeuchi, Akira Ichihara, Kenta Mikuriya and Akihiko Nakano

doi:10.1038/nature04737

See also: Editor's summary


Increased cell-to-cell variation in gene expression in ageing mouse heart p1011

Rumana Bahar, Claudia H. Hartmann, Karl A. Rodriguez, Ashley D. Denny, Rita A. Busuttil, Martijn E. T. Dollé, R. Brent Calder, Gary B. Chisholm, Brad H. Pollock, Christoph A. Klein and Jan Vijg

doi:10.1038/nature04844

See also: Editor's summary


Smad4 signalling in T cells is required for suppression of gastrointestinal cancer p1015

Byung-Gyu Kim, Cuiling Li, Wenhui Qiao, Mizuko Mamura, Barbara Kasperczak, Miriam Anver, Lawrence Wolfraim, Suntaek Hong, Elizabeth Mushinski, Michael Potter, Seong-Jin Kim, Xin-Yuan Fu, Chuxia Deng and John J. Letterio

doi:10.1038/nature04846


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Naturejobs

Prospect

Prospect p1021

Guidelines for physician-scientists call for training reform.

Paul Smaglik

doi:10.1038/nj7096-1021a


Special Report

Rules rule p1022

Regulatory affairs is a young profession that's already making its mark in the world of drug development, where one false move can bring years of research to an unwelcome end. If your skills include communication and leadership, it may be for you, says Hannah Hoag.

Hannah Hoag

doi:10.1038/nj7096-1022a


Career Views

Paul Gilna, executive director, Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis (CAMERA) project, San Diego, California p1024

Paul Gilna moves on to tackle ocean microbes.

Virginia Gewin

doi:10.1038/nj7096-1024a


Lessons from the jungle p1024

A trip to Africa inspires future graduate study.

Ayres Christ

doi:10.1038/nj7096-1024b


Write and wrong p1024

Manuscript writing presents challenges.

Katja Bargum

doi:10.1038/nj7096-1024c


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Futures

Check elastic before jumping p1026

Paralysis of the senses, temporarily.

Neal Asher

doi:10.1038/4411026a


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