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Nature 441, 774-778 (8 June 2006) | doi:10.1038/nature04845;
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Nuclear pore association confers optimal expression levels for an inducible yeast gene
The organization of the nucleus into subcompartments creates microenvironments that are thought to facilitate distinct nuclear functions. In budding yeast, regions of silent chromatin, such as those at telomeres and mating-type loci, cluster at the nuclear envelope creating zones that favour gene repression.
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