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News and Views
Nature 441, 702-703 (8 June 2006) | doi:10.1038/441702a; Published online 7 June 2006
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Neurobiology: Extending influence
Eve Marder1
Abstract
Rather than merely firing in a digital on–off fashion, vertebrate neurons may have an analogue aspect to their signalling too — a finding that will not surprise many who have worked on invertebrate neurons.
Much of what we know about electrical signalling in the brain comes from extracellular recordings that detect when a neuron is firing action potentials. These recordings do not, however, provide continuous monitoring of the fluctuations of membrane potential, and do not capture sub-threshold changes in membrane potential such as those caused by individual synaptic events.
- Eve Marder is at the Volen Center and Biology Department, Brandeis University, 415 South St, Waltham, Massachusetts 02454-9110, USA.
Email: marder@brandeis.edu
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