Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 441, 581-582 (1 June 2006) | doi:10.1038/441581a; Published online 31 May 2006
Open Innovation Challenges
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
- More Challenges
- Powered by:
nature jobs
Postdoctoral Positions
- Meharry Medical College
- Nashville, Tennessee, USA
Assistant or Associate Professor of Neurobiology
- Medical College of Georgia
- Augusta, GA United States
Virology: HIV goes nuclear
Abstract
HIV-1 replicates itself by integrating into its host cell's DNA. Studies in cell culture reveal that nuclear-membrane proteins aid engagement of the viral DNA with that of its host before integration.
Rather than going to the trouble of replicating its own genome, human immunodeficiency virus type 1 (HIV-1) inserts a DNA copy of its genome into that of its host so that the virus is reproduced during host-cell division (Fig. 1).
- Min Li and Robert Craigie are in the Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
Email: bobc@helix.nih.gov
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
LAP2α and BAF collaborate to organize the Moloney murine leukemia virus preintegration complexThe EMBO Journal Article (24 Nov 2004)
The inner-nuclear-envelope protein emerin regulates HIV-1 infectivityNature Letters to Editor (01 Jun 2006)
Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assemblyThe EMBO Journal Article (10 Jan 2007)
See all 8 matches for Research