FIGURE 3. Nonlinear effects in an amino-acid mediated aldol reaction.
From the following article:
Thermodynamic control of asymmetric amplification in amino acid catalysis
Martin Klussmann, Hiroshi Iwamura, Suju P. Mathew, David H. Wells, Jr, Urvish Pandya, Alan Armstrong & Donna G. Blackmond
Nature 441, 621-623(1 June 2006)
doi:10.1038/nature04780
Product enantiomeric excess expressed as a fraction of that obtained using enantiopure amino acid versus amino acid enantiomeric excess in the aldol reaction of equation (1) carried out in N,N-dimethylformamide (DMF) at ambient temperature using serine (circles), leucine (down triangles), alanine (uptriangles), valine (diamonds), and threonine (squares). Percentage product ee values found for the enantiopure catalysts are given.
