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Nature 441, 532-536 (3 May 2006) | doi:10.1038/nature04794;
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Rec8 phosphorylation and recombination promote the step-wise loss of cohesins in meiosis
During meiosis, cohesins—protein complexes that hold sister chromatids together—are lost from chromosomes in a step-wise manner. Loss of cohesins from chromosome arms is necessary for homologous chromosomes to segregate during meiosis|[thinsp]|I.
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