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Figures and Tables

From the following article:

Hypoxia signalling in cancer and approaches to enforce tumour regression

Jacques Pouysségur, Frédéric Dayan and Nathalie M. Mazure

Nature 441, 437-443 (25 May 2006)

doi:10.1038/nature04871

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

VEGF-A and angiopoietin-2 are key angiogenic factors induced by hypoxia.

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Figure 2

Oxygen sensors contribute to the destruction and inactivation of HIF-1alpha.

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Figure 3

Working model of two sets of HIF-1-regulated genes.

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Figure 4

Hypoxia meets the mTOR pathway.

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Figure 5

Hypoxia-induced loss of E-cadherin through the lysyl oxidase–Snail activation pathway.

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Figure 6

Intracellular-pH-regulating systems as potential anti-cancer targets.

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