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Figures and Tables

From the following article:

Identification of a tumour suppressor network opposing nuclear Akt function

Lloyd C. Trotman, Andrea Alimonti, Pier Paolo Scaglioni, Jason A. Koutcher, Carlos Cordon-Cardo and Pier Paolo Pandolfi

Nature 441, 523-527 (25 May 2006)

doi:10.1038/nature04809

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Pml status dictates carcinogenesis in Pten+/- mice.

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Figure 2

Pml loss leads to an increase in pAkt in vivo.

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Figure 3

Pml deficiency leads to increased nuclear pAkt localization and function in vitro and in vivo.

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Figure 4

Pml affects PP2a activity towards pAkt.

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