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Nature 441, 262 (18 May 2006) | doi:10.1038/441262a; Published online 17 May 2006
Open Innovation Challenges
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Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
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Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
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How does a painkiller harm the heart?
Meredith Wadman
It was Garret FitzGerald, the chair of pharmacology at the University of Pennsylvania, who first proposed that the painkiller Vioxx and its cousins might cause heart attacks by tipping a crucial hormonal balance. So neither of two attention-grabbing data sets published this month has come as a great surprise to him, despite the implications the data are likely to have for the 11,500 lawsuits from former patients that dog the drug's manufacturer, Merck.
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