Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Article
Nature 441, 239-243 (16 April 2006) | doi:10.1038/nature04721;
Open Innovation Challenges
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
- More Challenges
- Powered by:
nature jobs
Sr. Scientific Manager / Chief Scientific Manager- Discovery Metabolism and Pharmacokinetics (MAP)
- Syngene International
- Bangalore, Karnataka 560099 India
Copy Editor
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity
A common viral immune evasion strategy involves mutating viral surface proteins in order to evade host neutralizing antibodies. Such immune evasion tactics have not previously been intentionally applied to the development of novel viral gene delivery vectors that overcome the critical problem of anti-vector immunity.
&
Abstract
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
