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Nature 441, 166-168 (11 May 2006) | doi:10.1038/441166a; Published online 10 May 2006
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Immunology: What does it mean to be just 17?
Cristina M. Tato1 & John J. O'Shea1
Abstract
For a long time it was thought that there are only two types of T helper cell. But it is becoming clear that there may be other lineages that influence inflammatory responses in certain circumstances.
T cells are a workhorse of the adaptive immune system, with the job of orchestrating defences against microbial invasion. A sub-category of T cells, T helper cells, defends against microbes but also causes trouble by inducing inflammation in immune-mediated diseases.
- Cristina M. Tato and John J. O'Shea are in the Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, Bethesda, Maryland 20892-1820, USA.
Email: tatoc@mail.nih.gov;
Email: sheaj@arb.niams.nih.gov
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