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Nature 441, 22-23 (4 May 2006) | doi:10.1038/441022a; Published online 3 May 2006

The quiet rise of the clinical contractor

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More and more drug trials are being farmed out to contractors, but who's benefiting from the change? Meredith Wadman investigates.

When a big US drug company needed to get a late-stage breast-cancer trial launched quickly some years ago, it turned to PRA International, one of a dozen major contract-research organizations (CROs) that now permeate the worldwide drug industry.PRA is headquartered in a nondescript office building outside Washington, DC.