Figures and Tables

From the following article:

A small-molecule screen in C. elegans yields a new calcium channel antagonist

Trevor C. Y. Kwok, Nicole Ricker, Regina Fraser, Allen W. Chan, Andrew Burns, Elise F. Stanley, Peter McCourt, Sean R. Cutler & Peter J. Roy

Nature 441, 91-95(4 May 2006)

doi:10.1038/nature04657

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Figure 1

The molecular structures of nemadipine-A, nemadipine-B, felodipine, and the core 1,4-dihydropyridine (DHP) structure.

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Figure 2

Embryos raised on nemadipine hatch with Vab defects.

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Figure 3

Animals grown on the nemadipines are Egl.

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Figure 4

EGL-19 functions redundantly with both UNC-2 and CCA-1.

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Table 1

Biological properties of L-type calcium channel antagonists and DHP analogues

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Table 2

Genetic suppressors of nemadipine-induced defects

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