Tumour cells tend to carry many gene mutations, but at a potential cost to their overall fitness. Studying the interactions between genes on a large scale could be a way of identifying the chinks in the tumour cell armour.
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Kaelin, W. Divining cancer cell weaknesses. Nature 441, 32–34 (2006). https://doi.org/10.1038/441032a
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DOI: https://doi.org/10.1038/441032a