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Nature 440, 1099 (27 April 2006) | doi:10.1038/4401099a; Published online 26 April 2006

Flu-vaccine makers toil to boost supply

Carina Dennis

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Stock shortfall highlights need for alternative strategy.

The threat of a bird-flu pandemic is forcing vaccine developers to make tough choices about the types of vaccine to pursue. Many advanced trials are testing vaccines that use disrupted viruses, which have few side effects.