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Nature 440, 1233-1237 (27 April 2006) | doi:10.1038/4401233a; Published online 26 April 2006

Open Innovation Challenges

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Gene expression: An expression of interest

Laura Bonetta1

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Understanding the regulation of gene expression in stem cells and neurons, and finding ways to manipulate it, are important challenges. Laura Bonetta searches out the tools for the job.

Researchers face a difficult task as they try to realize the therapeutic potential of stem cells and neurons. To better understand how to manipulate these cells, they need to monitor the gene-expression patterns, as well as working out how these genes are controlled.