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Supplementary information

From the following article:

Independent evolution of bitter-taste sensitivity in humans and chimpanzees

Stephen Wooding, Bernd Bufe, Christina Grassi, Michael T. Howard, Anne C. Stone, Maribel Vazquez, Diane M. Dunn, Wolfgang Meyerhof, Robert B. Weiss and Michael J. Bamshad

Nature 440, 930-934 (13 April 2006)

doi:10.1038/nature04655

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Supplementary Figure 1

This file contains a JPEG of Supplementary Figure 1: Schematic of artificial expression constructs.

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Supplementary Figure 2

This file contains a JPEG of Supplementary Figure 2: Schematic of constructs used for testing receptor response to PTC.

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Supplementary Figure 3

This file contains a JPEG of Supplementary Figure 3: Transfection and expression of TAS2R38 in HEK cells.

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Supplementary Figure 4

This file contains a JPEG of Supplementary Figure 4: Membrane localization and functional characteristics of the AGG-chTAS2R38 (-99aa) construct.

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Supplementary Figure Legends

This file contains the Supplementary Figure Legends.

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Supplementary Notes 1

This file contains the raw genotype and phenotype data.

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Supplementary Notes 2

This file is a text file conversion of an SAS (Statistical Analysis System) file that generates summary statistics describing the raw data.

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Supplementary Notes 3

This file is a text file conversion of an SAS (Statistical Analysis System) file used to test for differences in response between TAS2R38 heterozygotes and homozygotes.

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Supplementary Notes 4

This file is a text file conversion of an SAS (Statistical Analysis System) file used to test for association between TAS2R38 genotype and PTC sensitivity phenotype.

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Supplementary Notes 5

This file is a text file conversion of an SAS (Statistical Analysis System) file used to test for differences in response of predicted tasters and nontasters between the test and control treatments.

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